Due to my 17p deletion, my doctor started Imbruvica 4 months ago. My CT this week has shown marked improvement from the last one, my lymph nodes greatly reduced in size. Also my lab values are best they have been since before my diagnosis 8 years ago. We are excited about this response, but not sure what to expect. My doctor says he's not sure how long I will remain on the meds. Has anyone else had this experience?