I recently had to stop my Ibrutinib for three weeks while I was in hospital having surgery in the form of a total hip operation. I was expecting, following the operation and three weeks off the drug to be back where I started two years ago or almost as I had heard that continuity in taking Ibrutinib was important. My levels prior to the operation were WBC 12 , platelets 150 and HG 160.. Following surgery these had fallen a little for two or three days but the WBC had gone down to 4.5 , the platelets have doubled to 350 and the haemoglobin is almost back to 160.. Can anyone offer an explanation for this apparent good news bringing all my levels within the normal range. The only downside to this is a DVT requiring a high dose of blood thinning but I am compensated by a successful operation long overdue as I had been on sticks for thirty years, I am now planning all the things I could not do including playing with the grandchildren and even a simple walk down the lane.