For those interested, the March issue of Oncology Journal, provided by the Cancer Network, has quite a few articles relevant to CLL and associated blood disorders, some of which have been previously posted about. Here are some more:
Novel Biologic Agents for Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia—Part 1
Covers the latest developments in anti-CD antibody drugs for CLL, Diffuse Large B Cell Lymphoma and other B-cell malignancies:
The Era of Immuno-Oncology: Are We There Yet?
Editorial overview of the related discussion in the March issue: cancernetwork.com/oncology-...
The clever design of blinatumomab, an antibody with dual specificity for CD19 and CD3, which allows cytotoxic T cells to effectively kill B-cell clones gets mention in both articles. Watch for more developments in this area, as researchers aim for more selective targeting and greater effectiveness.
Photo: Masked Lapwing. These birds lay their well disguised eggs in a nest on the ground and are very good at distracting potential predators from the nest by various means, including faking a broken wing while running away from the hard to see nest. Sometimes it is possible to see the spur on their wing as is shown in the photo in the link below, hence their other common name - the Spur Winged plover: