Prompted by the end of the thread that Neil started recently on ABT199, you all reminded me about clonal evolution.
I've previously put that one on the “too difficult pile”, but time now, I think, to engage the grey matter.
Any chance you could all add your best references, and thoughts, to this thread.
Here’s just an initial one I found, dating from early last year:
. . . over 100 references at the end of that one.
Something a little easier to start with, Peter Nowell, referenced in the above, appears to have started the ball rolling in 1976. Here’s a short potted history from the man himself:
Peter’s last paragraph makes optimistic reading.