Antifungals Cut Risk of Invasive Infections in Neutropenic Patients

Antifungals Cut Risk of Invasive Infections in Neutropenic Patients

If you are Neutropenic, you may wish to discuss these new findings with your doctor.

Patients receiving therapy for haematological malignancies have a higher risk of invasive fungal infections (IFIs). Antifungal prophylaxis is an effective strategy against IFIs.

The study found that ...

Antifungal prophylaxis was more effective than no prophylaxis/placebo in reducing IFI risk.

Posaconazole was also found to be more effective than no prophylaxis/placebo in reducing all-cause mortality. The drug had the highest probability of being the most effective agent in reducing IFI risk and all-cause mortality.

The researchers say the results are consistent with the recommendations made in previous studies. In fact, the order of antifungal preference "matches that recommended in a recent study of the German Society for Haematology and Oncology."

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Abstract

jac.oxfordjournals.org/cont...

~chris

2 Replies

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  • Thanks Chris,

    That's another addition to my reference folder for when treatment is needed.

    Nice picture too. Is that a cornflower?

    Neil

  • I have thought for years that opportunistic fungal infections are under studied in CLL, and probably under treated, especially in end stage.

    Yup a cornflower in the Ottawa countryside...

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