Fibroscan .. a potential thought for some seeking more info.

I had a good read today and found out some intetesting things about fibroscans and transient elastography that I thought Id share for anyone down the road seeking info. According to a really well done study it would seem that those with Acute Hepatitis can get some false reads on a liver stiffness test. Basically the the tissue changes that happen in the liver as a result of necro-inflamation caused by the hepatitis can drastically change the stiffness of the liver (sometimes up to kpa results that would suggest cirrhotic and severe choleostasis) until the inflamation ceases and resolves. This has been proven by conducting multiple fibroscan tests over time on a patient with Alcoholic hepatitis and monitoring how the KPA results lowered in correlation with the liver enzymes lowering alongside it. It is therefore recommended that fibroscan tests not be conducted while Alt levels are 100 or above. This may explain why some of the folks on this site have seen drops in kpa readings o er the years on their Fibroacan results. Its possible that as opposed to the thought that a cirrhotic liver is reversing it is actually the resolving of necro inflamattion and that the liver was not cirrhotic to begin with. Just an interesting thought and possibly something we can all ask a dr when tests and diagnosis of cirrhosis seem to be not clearly conclusive.

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Apologies I meant to say "It is therefore recommended that fibroscan tests not be conducted while Ast levels are 100 or above." Not ALT

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Hi Phoenix,

Can you please share with us the clinical reference for this? We would be very interested to read about it.

Many thanks,

Trust1

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Sure ncbi.nlm.nih.gov/pmc/articl...

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Particularily the area of necroinflamatory affects

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Thank you

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No problem. Did you get to review it?

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Not yet but it is on my list!