Anyone been through the intense itching often associated with liver problems? Have you any advice as it is driving me crazy. I apply Menthol Aqueous Cream 5% but it's effect is short lived..and anti histamine Chlorphenamine 4 mg x 3 times a day also seems ineffective. My doctors seem dismissive putting it down as untreatable due to liver problems. i have heard that combining H1 and H2 inhibitors help patients with intense itching if taken in large doses.