2.5yrs ago my wife had treatment and is now on tamoxefin. our marriage is in crisis. she suddenly ask me to leave the house, things were difficult. i wasnt coping with the changes in her moods and change in how she behaved with me. i dont think its just the drug..it may be due to the drug affecting her hormone levels. so 7 weeks on she still has multiple mood changes, wont let me see the children. and doesnt think there is anything wrong with her. anyone having similar issues please tell me...desparate husband who loves his wife and doesnt like seeing her hurting like this.