Breast Pain and tender

My mother (Age 52) was diagnosed for metastatic renal cell carcinoma in April 2014..cancer had spread to lung and left lower para-aortic iliac lymph nodes …her treatment was started from May 2014 , with SUTENT 50mg (4 weeks on and 2 weeks off )and she is still under treatment with dose reduced to 25mg..On May 2015, her PET scan report showed reduction in tumor (Nodules in right lung which was 25mm was reduced to 14mm)..

Due to side effect of Sutent she had foot sore, which was very painful she was unable to of my cousin in US suggested me to go for Udderly Smooth foot cream which has shown gud effect on chemo patients suffering from foot syndrome…just 10 days back I purchased tat cream and applied to her feet.. From past 2days she has pain in right side of breast, she feels pain only if touched..Udderly smooth cream contain paraben, and I heard it causes breast cancer…I m worried and tensed, is it true tat my mother is getting pain due to this cream?? She is using this cream from past 10days..Exposure to paraben for 10days can cause breast cancer?

After starting treatment with SUTENT her menstrual cycle was irregular like 6 months once or 3months once…Before Treatment she had regular mensutral cycle..plz reply me I am worried, is it a sign of breast cancer???

8 Replies

  • I do not think that your mother is getting pain due to that cream. There might be other reasons. Don't worry, this is not breast cancer either. As for the cause of pain, it's difficult to judge without understanding and seeing; your doctor will be in best situation to guide you there.

    In the meanwhile, if the pain is a little more, please do cover her with some pain killers so that she is comfortable.

  • Dear Anu,

    Your mom is battling really well with the cancer from May 2014 till date... hats off to her and no doubt this wonder drug is proving to be really quite effective for her.

    Udderly Smooth Udder Cream contains:

    Deionized water, stearic acid, Peg-2 Stearate, propylene glycol, isopropyl myristate, dimethicone, lanolin oil, mineral oil, triethanolamine, allantoin, methylparaben, propylparaben, fragrance

    What are parabens?

    Parabens are among the most commonly used preservatives in cosmetic products. The most common parabens used in cosmetic products are methylparaben, propylparaben, and butylparaben. Typically, more than one paraben is used in a product, and they are often used in combination with other types of preservatives to provide preservation against a broad range of microorganisms

    Are there health risks associated with the use of parabens in cosmetics?

    The Cosmetic Ingredient Review (CIR) reviewed the safety of methylparaben, propylparaben, and butylparaben in 1984 and concluded they were safe for use in cosmetic products at levels up to 25%. Typically parabens are used at levels ranging from 0.01 to 0.3%.

    In September 2005, the CIR decided to re-open the safety assessment for parabens to request exposure estimates and a risk assessment for cosmetic uses. In December 2005, after considering the margins of safety for exposure to women and infants, the Panel determined that there was no need to change its original conclusion that parabens are safe as used in cosmetics.

    FDA is aware that estrogenic activity in the body is associated with certain forms of breast cancer. Although parabens can act similarly to estrogen, they have been shown to have much less estrogenic activity than the body’s naturally occurring estrogen.

    In a review of the estrogenic activity of parabens, (Golden et al., in Critical Reviews in Toxicology, 2005) the author concluded that based on maximum daily exposure estimates, it was implausible that parabens could increase the risk associated with exposure to estrogenic chemicals.

    FDA believes that at the present time there is no reason for consumers to be concerned about the use of cosmetics containing parabens. However, the agency will continue to evaluate new data in this area. If FDA determines that a health hazard exists, the agency will advise the industry and the public, and will consider its legal options.

    With regards to your moms menstrual cycle, she is probably going through menopause.

    My last comment may seem a bit rude, but your mom already does have metastatic renal cancer which has spread (Stage IV), that is a greater and bigger worry than the current breast pain scare.

    Breast Pain does not equate to Breast cancer.

    You may seek your oncologists opinion as well, who may examine your moms breasts and to reassure you, may organise a Mammogram (This should be least of the worries)

    Its important for your mom to be on Sutent and if I were you, I d continue with the cream.

    With Best Wishes

    Dr Rohit Malde MD, DNB, FRCR (UK)

    Consultant Clinical & Radiation Oncologist

    BNH HCG Mumbai

  • Thank you so much for ur kind reply Doctor..

    Yesterday I could feel a small lump on my mother breast, so I took her immediately to HCG hospital and explained everything to our Oncologist..She said not to worry and did needle aspiration and sent the samples for testing…Results ill be available after 2 days

    Since our Oncologist doesn’t have enough time to speak with us as she ill be very busy I want to get some doubts cleared here...kindly don’t mind…

    We did whole body PET Scan just 2 months back i.e May 18th 2015, it didn’t show any tumors elsewhere expect in Lungs..i hope if FNAC test turns to be positive it won’t be in last stage

    If its is in initial stage, can it be cured?? Will this interfere with treatment of renal cell carcinoma??

  • We surely will clear your doubts, but we also request that you must insist your oncologist to help you with your doubts as well. The question is not whether the doctor has the time to do it. The questions is whether he or she wants to do it or wants to give time to a patients. If a doctor wants, however busy they are, they can easily find time. It doesn't take more than 5 to 10 mins for an Oncologist to solve 80 percent of patients queries. if your doc doesn't answer to your satisfaction or doesn't give you time to your satisfaction , you might want to consider to change your doctor simply because I would not let someone treat my mother without telling me all details and clarifying my queries. I can very well understand your situation which is most common all over India. There are many oncologists who are insensitive and just don't bother about whether the patient and relatives have understood and will they go home satisfied or not. That's the whole reason we started this forum, to encourage patients to help each other with problems they face during treatment and to share it with others and to encourage others when others feel down.

    Asking questions here won't help simply because decisions in cancer are not based only on reports like biopsy or pet scan etc. but on thorough assessment of the patient and most importantly, understanding the biology and trend of a patients' cancer, which is different for each and every patient and which can be known in detail only by the treating oncologist. There is much more to a cancer patient than just some reports on paper. This forum is aimed at providing supportive care and encourage self help between patients with doctors to help them and guide them. For reasons explained above, this forum cannot be a place for second opinions or getting professional medical opinions.

    As for your doubts, breast cancer in early stages is definitely curable. However, please understand that your mother has no threat from breast cancer at all (and from what you describe, I don't even think she has breast cancer at all). She is already suffering from stage 4 renal cancer; so another cancer in early stage may be curable but the already existing stage 4 cancer is not.

  • Dear Doctor

    We have received 2 reports for FNAC test from different lab..

    One report says no evidence of malignancy but other report says malignancy..

    doctor suggested us to go for biopsy..i am worried plz do help me in understanding this result

    Report 1: (MS Ramaiah hospital)

    Cellular smear reveal cohesive ductal cells and sheets of apocrine cells

    Backgrouund shows fair number of neutrophils and cyst macrophages on the clear background

    No evidence of malignancy seen in the material studied

    Impression : features are in favour of inflammed cyst

    Report 2: (HCG)

    •Smears studies show clusters of cells in papillary configuration with abundant granular cytoplasm

    •Nuclei is round. Background show acute inflammatory exudates.

    Impression: Possibility of metastatic carcinoma is considered

    Biopsy is necessary

    please help me doctor

  • It's better to go for a biopsy and send it to a good pathologist to do immunohistochemistry to tell us about the lump in details. Without that, we will not know whether it's a new breast tumour or has possibly spread from the renal cancer.

  • Dear Doctor

    We received biopsy report and it says

    •Apocrine metaplasia

    •No evidence of ADH, DCIS or invasive malignancy, B2

    Next Monday we have appointment with doctor. I hope there is nothing to worry with this report as this is benign tumor… am I correct doctor??

    Or should we go for any other testing??

  • The report is fine and suggests that this is not cancer. So nothing to worry about.

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