Hi, I am ImmunePoison. I picked that name because it feels like my immune system has been permanently altered by a single shot of the drug, Prolia. I am a retired writer, age 70. When I was 30 I went through weight loss surgery as it was known then as a JI Bypass which makes the small intestine about 16 inches long. When I was 40 I contracted Chronic Fatigue Immune Dysfunction Syndrome and Fibromyalgia. 2 years ago in January I received a Prolia shot for osteopenia. Unfortunately the drug was new and the contraindication for giving the shot to someone with bowel surgery was buried on page 14 of 30 pages of information by the manufacturer, Amgen. My doctor did not know. Since the shot I have been plagued by severe bowel cramping, watery diarrhea, weight loss of 15 lbs, long cold spells, followed by almost continuous hot flashes. These spells which can last 3 days, have been getting less frequent, but it is still something I must cope with every day. I am miserable and have not been able to get any answers other than Prolia affects the immune system and a lot of studies show that the immune system is often affected by what happens in the gut. I am searching for how this is affecting my body, and Why, but also for something that might help my body cope with the changes brought about by one little shot that took 5 seconds to give and is not affecting my whole life.