Enteric-coated Aspirin, anyone? - British Heart Fou...

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Enteric-coated Aspirin, anyone?

STEMI_Dave profile image
6 Replies

My GP changed my prescription from dispersible to Enteric-coated Gastro-resistant Aspirin to try to deal with morning queasiness, but there's no instructions from him or the dispensing pharmacy on the best time to take these. As they are absorbed differently, has anyone got any experiences, e.g. before, during, or after food.

Background: up until recently my timing was wake up, Lansoprazole, 30mins, breakfast, 30 mins, then dispersible Aspirin, Bisoprolol, and Eplerenone.

Some technical reading here: pubmed.ncbi.nlm.nih.gov/277... which suggests that timing was important in that study population.

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6 Replies
Lowerfield_no_more profile image
Lowerfield_no_more

I take enteric coated low dose aspirin and have done since the dispersible would have caused me gastric problems. They are not digested in the stomach due to the coating but further down the digestive system and so there is no need to be cautious about taking them with food, but if you want to I am sure that would be OK. Otherwise in my view any time of the day is fine so long as its more or less the same time each day, although the NHS advise not to take them within 2 hours of any indigestion remedy. I take mine in the middle of the day. Apparently there is some evidence to suggest that they are slightly less effective than the dispersible sort, but in my case that is an acceptable trade off against the problems I would face if took the dispersible type.

Happyrosie profile image
Happyrosie

as Lowerfield says. My husband has been on these for some 22 years and takes Lans. (Or something similar) then 30 to 60 min break then all the other tabs including enteric coated aspirin.THEN breakfast.

Weetabixie profile image
Weetabixie

Hi STEMI _Dave, I was on dispersible but was changed to Enteric coated as I have GORD or GERD and could not tolerate it. I take lansaprazole then half hour later I take clopidogrel, aspirin and bisoprolol with breakfast. Hope that helps 🤗

annpavitt250448 profile image
annpavitt250448

My prescription for enteric coated aspirin says take them with it just after food, so I take mine at breakfast. Got my doctor to change mine over from dispersable as I was getting acid reflux again Have mild erosive gastritis. When I went for pre assessment for getting a total knee replacement found I was iron deficient. So had iron infusion, c.t. Colonography and endoscopy which showed up no sign of bleeding, so I am convinced the aspirin and pantoprezole I take are the cause.

STEMI_Dave profile image
STEMI_Dave in reply to annpavitt250448

Thanks! You have an interesting point about iron deficiency. I was wondering if PPIs (pantoprezole in your case, lansoprazole in mine) affect nutrition uptake.

annpavitt250448 profile image
annpavitt250448

Got a g.p appointment on Monday to discuss scan results, not that he can tell me anything I didn't already know, having had an endoscopy 6 years ago which picked up the gastritis ( caused I think of years taking diclofenic) before I had a hip replacement 22 years ago. Also had co!endoscopy last Feb which just picked up a few pockets of diverticular. I intend to ask whether the iron deficiency could be caused by the p.p.I and aspirin. Also going to ask if I could be vitamin B12 deficient, as I understand the p.p.I can deplete your vit. B12 and also cause not to absorb iron so efficiently

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