enteric coated aspirin

[Purpled]

curious how many people take this on an empty stomach. I have always taken after meals but told this is wrong.

[Hidden]

My understanding is, unlike dispersible aspirin which should not be taken on an empty stomach, it really doesn't make any difference when you take coated aspirin whether with or without food or on an empty stomach. Anyway I usually take my coated aspirin after breakfast (with the PPI before) and have not had any problems

[Hidden]

Hello

I take coated Aspirin and still take it when I have eaten I never knew that they say you should not who told you ?

You have got me wondering now I shall ask my Doctor maybe I am taking it wrong x

[Purpled in reply to Hidden]

hi, yes I always took it after meals but had to spend overnight in A&E. Doc looking at meds asked if I took the EC aspirin 30 mins at least before food as that’s when I should be taking it.

[Hidden in reply to Purpled]

Hello

Sorry you ended up in A&E hope you are alright now

Well that is interesting I may have to start taking it 30 mins before then I shall ask my Doctor and if she says either way it does not matter I shall give it a go to x

[Purpled in reply to Hidden]

Please let me know what your Doc says, this Doctor says taken with food it reduces the effect it has on platelets.

[Hidden in reply to Purpled]

Hello

I will she is supposed to be phoning tomorrow so I will put it on the list which is growing by the minute x

[Hidden in reply to Purpled]

Hello

I struggled to find the post again and was getting in a panic but here it is

So I spoke to her I think she feels I have lost the plot now altogether as I did ask the question to which she replied she had never heard of this before

She asked why I was asking and I just said O someone was told when they were in Hospital that is how they should take them

She said well I cannot say I have come across that before or been made aware of it, so I said well do you think I should take them half an hour before food then to which she said well you can do I have no problem with you doing that

So to sum it up she never has heard you should but you can take them half an hour before and as that is what they said in the Hospital I would do what they told you and I am going to do the same and as long as it does not upset my stomach anymore than my stomach is already upset I shall carry on doing it to

Hope you have had a nice day x

[Purpled in reply to Hidden]

Oh my goodness, I hope I havn’t put you on the spot. It just shows though what a difference there is between Doctors. Take care x

[Hidden in reply to Purpled]

Hello

No she knows what I am like

Yes it is strange at times how Doctors are different with their views

Have a lovely weekend x

[Heartfairy in reply to Hidden]

Good to see you back ❤️🧚🏼‍♀️

[Hidden in reply to Heartfairy]

Thank You

Hope you are doing ok x

[Heartfairy in reply to Hidden]

Yep I’m ok thanks for asking. You look after yourself ❤️🧚🏼‍♀️

[Hidden in reply to Heartfairy]

x

[Manhattan1]

i take the 75mg dispersible aspirin after breakfast

[Purpled in reply to Manhattan1]

Yes that’s fine this advice was just for the enteric coated ones.

[Becdan]

I always take it after breakfast with my other meds. Have never been told otherwise. I would be interested to know what difference it makes.

[Purpled in reply to Becdan]

apparently if it’s taken with food it has been found to reduce the effect it has on the platelets.

[Hidden in reply to Purpled]

Coated aspirin is specifically designed not to dissolve within the stomach, so that it passes through without causing irritation to the stomach lining, which can occur with dispersible aspirin. Then after it has passed though intact it subsequently travels through the remaining part of the digestive system with digesting food where the coating is stripped off due to the decreasing acidic environment and the aspirin is released to be absorbed through the gut wall. So it appears to me that the coated aspirin tablet will be in contact with food matter irrespective of when the tablet was consumed relative to food being eaten. The question of the effectiveness of coated aspirin is one of comparison to dispersible aspirin and seems to revolve around the fact that dispersible is quickly absorbed in the stomach after it has been taken, whereas a whole tablet may not be completely and effectively absorbed within the gut, so some of the intended benefit is lost.

And the instructions for dispersible aspirin is to take it with or just after food so as to moderate the irritation it causes to the stomach wall.

[Pollypuss in reply to Hidden]

yes I take mine with porridge at night . I get large bruises so I feel sure it must be working !

[Andyd57 in reply to Hidden]

Your wasted on here 😇

[CyclingTime]

I am in dispersible aspirin and the clear instruction is to take Lanzaprazole first 30m before food and then take the aspirin

I only mention it as I did not see anyone mention Lanzaprazole or it's other types here

[Swalecliffe88]

I think the question here is. What is the reason for you taking the aspirin. Was it prescribed following a heart event or as a precaution from age or family history, or, just your choice ? It is nearly 10 years ago since I was first prescribed aspirin following diagnosis of angina. But was told when I asked about taking the coated one by my consultant, that this type is not appropriate. And for the reason quoted below. Non coated disperses in stomach and is absorbed into blood stream fast and in high concentration. The coated disperses in the gut and therefore not as immediate or as effective for heart patient needs but ok for pain relief needs. A dissolvable one is often used by paramedics given to dissolve under the tongue when attending suspected heart attack victims also. If that helps ? Best to ask consultant or BHF heart nurse, not necessarily GP as not all are totally conversant with heart issues. Although this is one of the oldest and most used medications. As to when to take. There has been research done recently that indicates a number of heart related medications including aspirin is better taken at night. As it is something to do with how the body absorbs and uses these to best effect.

[Hidden in reply to Swalecliffe88]

I take coated aspirin for the simple reason that I have had serious stomach bleeds caused by NSAIDs and have other gastro related problems. So for me, and possibly others similarly affected, the most appropriate way to take low dose aspirin is the coated sort, although I accept the possibility of reduced effectiveness compared to dispersible, and the transfer of irritation risk from the stomach to further along the digestive system. However I have been taking coated aspirin for almost 5 years, and have not noticed any adverse effects, and certainly if increased bruising is an indicator coated aspirin is doing the job intended!

[Purpled in reply to Hidden]

Thanks for that, I have been having stomach issues as well and have done in years gone past which is why I am now taking the enteric coated which I have been taking after my breakfast until doc told me otherwise.

[Becdan in reply to Hidden]

Hello LowerField

I am also taking the coated tablets because of gastro problems and I am also taking Clopidogrel. I don't seem to get as much heartburn or acid reflux since taking the coated tablets but it hasn't alleviated it completely yet🤞 Do you take yours with, before or after food.

Thanks

[Hidden in reply to Becdan]

I take lansoprazole (for reflux disease) before breakfast then aim to take the aspirin after breakfast with one other med. However sometimes I forget the second round and discover that later, occasionally at the end of the day when I take a final round of meds before bed. But on the 'forgetful' days don't notice anything unusual about how I feel.

[Becdan in reply to Hidden]

Thank you

[fishonabike in reply to Swalecliffe88]

i suspect that one of the studies you refer to at the end of you comment is "Does the timing of aspirin administration influence its antiplatelet effect – review of literature on chronotherapy" by Ewa Miciak-Ławickaet al - ncbi.nlm.nih.gov/pmc/articl...

It concludes that: "Recent studies suggest that a low dose of aspirin administered in the evening reduces COX-1 dependent platelet function in the morning in healthy patients. Future research with larger study groups is necessary to answer the question of whether ASA administered in the evening reduces the risk of cardiovascular events in the morning hours."

unfortunately it says nothing about taking it with, before or after food, and does not touch on the additional effect or not of enteric coating

[Purpled in reply to fishonabike]

I have not read any reports I was told by hospital doctor I should be taking 30 mins before my breakfast not after.

[fishonabike in reply to Purpled]

i would not expect you to have read the reports, but it would help if your doctor did! I know they can't read everything but some of the recommendations they make are based on very outdated information

[Heartattackvictim]

Here's an oddity: in the three occasions I've been in hospital (for 2 NSTEMIs and latterly bad angina) I was given the coated version and when discharged packed off with the dispersible version. I was given lansoprazole both in hospital and on discharge.

[Purpled in reply to Heartattackvictim]

mine were put on prescription by cardiologist but still put on ppi which I couldn’t take because of bad diarrhoea, I tried them all.

[fishonabike]

From the 2020 paper: "Bioavailability of aspirin in fasted and fed states of a novel pharmaceutical lipid aspirin (PL-ASA) complex formulation" by Dominick J. Angiolillo et al

The results of the current study demonstrate that PL-ASA can be taken with food with only minimal impact on overall drug exposure and bioavailability.

this translates as : it makes little difference on the antiplatelet effect whether you take aspirin with, before or after food

the main reason for taking enteric-coated aspirin is to reduce the risk of stomach damage - the risk is also reduced by taking a PPI (e.g. lansoprazole) and/or taking aspirin with or soon after food when the food offers some protection

some lucky people can take aspirin willy-nilly without damage to their stomach, but doctors can't take the chance that you are one of these, so they have to recommend measures to protect you

[Qualipop]

I take it but have never been told a specific time. I take it first thing when I get up and then have breakfast. As it doesn't dissolve until it reaches the intestine I see no reason to take with food. I recently asked when to take it if I forgot and was told any time as long as not within 12 hours of the next dose.

[Purpled in reply to Qualipop]

Oh yes perhaps the reason why he said 30 mins before breakfast to give it time to go down before getting mixed up with the food. Will have to ask my normal consultant next time I see him.

[wischo]

I live in Ireland and 75mg aspirin is on prescription only here. The GP will not prescribe the dispersible type and I doubt you could get them here anyway. Its all enteric coated aspirin and I have read the studies some of which claim that the coated ones may not dissolve fully in the gut. My GP pointed out to me that this is not really the case and that the enteric coated ones are equally effective. The reason that medics give an uncoated aspirin during a heart attack is the speed it enters your bloodstream is faster and they also tell you to chew it to make it even faster. With 75mg daily aspirin you will have a constant amount in your bloodstream and the only reason uncoated ones are used is because they are cheaper for the health services.

[Purpled in reply to wischo]

Interesting, I wonder how effective it is in reducing heart attacks.

[wischo in reply to Purpled]

I would imagine its as effective as aspirin can be or otherwise they would not market it. I think all 75mg daily aspirin were enteric coated some years ago in the UK but it was decided to dish out the plain ones due to financial costs to the NHS. Aspirin of either kind are quoted as may prevent heart attacks or strokes so not sure how many if any heart attacks they reduce. Read that Clopidogrel gives much better protection from blood clots which are what antiplatelets are meant to do. Probably better not to give it too much attention and let the experts deal with it.

[BlackGazelleHound]

On dischrge after HA in May 21 I was given Lanzoprazole to protect my stomach from ticagrelor and dispersible aspirin. However, after the statutary 12 months on Ticagrelor and as the Lanzoprazole did not agree with me, after duscussion with my GP I switched to enteric coated aspirin and stopped taking the Lanzoprazole. I have not had any problems with my stomach since this change.

[Purpled in reply to BlackGazelleHound]

that is good to hear.

[mumsastudent]

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