I have never had stomach problems.
In 2014/15 I spent a year on Ticagrelor and Aspirin, no stomach problems.
I have been on Aspirin ever since with no problems. I have now had Clopidogrel added AND a PPI with instructions to take in the morning.
But surely, the more common sense plan would be to take Aspirin and Clopidogrel at night after a large meal. Then no PPI would be needed?
Confused, as I hate taking unnecessary meds!
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Jump to repliesDear ChoochSiesta.
It sounds like that your Dr has put you on a standard and well tried combination of drugs that simply work for the majority of patients that have to take them, the blanket approach.
Thats not to say that yours can’t be tweaked to just you and your needs. Discuss this with your Dr or whoever placed you on these.
I take { as many } the same sort of combination as you, the PPi for me was because I had a history of ulcers.
I think that asking the right questions to the right people will get you a more personalised plan for your recovery, including the drug side.
Take care I hope you achieve your goals.
Sounds like a plan, thanks 👍
I must admit, I took the PPI when I thought it would suit me best, which is a 30mg late evening, aspirin gets taken in the morning with other meds and since I changed, I've never had a problem.My OH takes 2x 30 mg PPI, one morning, one evening as a precaution because of the cocktail of drugs she's on (45 pills/capsules per day)
The doctors do seem to throw them at people like confetti 😏
The theory is that you take the PPI to reduce acid production just BEFORE aspirin / Clopidogrel.My contention is line your stomach with a large meal instead.
Why tell the patient to take Aspirin / Clopidogrel on an emty stomach?!
I wasn't keen to take aspirin because of ulcers in the past but needed to. I never take any meds till I've eaten just to be safe.Personally I think we should decide for ourselves what suits us best.
As my Dr keeps telling me, we know our own body better than anyone.
The purpose of a PPI is to prevent the production of excess acid, not to “line the stomach”, so a large meal actually has the opposite effect of a PPI. Aspirin + Clopidogrel is a tried and tested combination to prevent the formation f stomach ulcers; as someone who has previously had 3 ulcers, I’d heartily recommend a PPI when taking any irritant such as Aspirin. As they say “prevention is better than cure”.
I see your point. Do you think a large evening meal is a decent protection when mixed up with Aspirin / Clopidogrel?
I can only speak from my own experience and recommend a PPI whilst taking Aspirin.
Update to previous Clopidogrel post
Cosmetic tattoo and aspirin 
Proton Pump Inhibitors 
