Hi -I just want to ask people's experience of being on these 2 drugs together and how long they take to work? I've been on infliximab since March and on Methotrexate since June -I was told it would take at least 6 months for the infliximab to work. I was put on these meds after my last major flare up in March and taken off cellcept which didn't work for me. I've also been on and off steroids for the past 2 years since diagnosis. I was put on 120mgs in Marcb and am now down to 7mgs, the thinking being to bring me down to a maintenance dose of 5mgs and the other meds should kick in. The problem is over the past 10 days or so I've been extremely tired ie worse than before and very down/depressed-bursting into tears etc. I'm also sleeping very badly. Is this steroid withdrawal or the disease I wonder -has anyone experienced this? I've been very positive all along but now the disease and everything seems to be overwhelming me and I can't cope. My family are getting impatient with me saying I am not thinking clearly. Sorry for long post I'm just a bit lost with this. If I thought it was just steroid withdrawal I might suffer on with it. Even though I managed to escape major organ damage despite being in a life threatening condition twice I still feel rubbish every day and it's getting to me. Again apologies for moaning I just wonder if people have had success with these drugs after a time. Thanks
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