Antibiotics

[PAP48]

Has anyone been prescribed Co-trimoxazole and Cefalexin 500mg to take together? I have a chest infection Klebsiella and have been prescribed the two antibiotics, however, I'm feeling quite unwell, shivery and then hot and not sleeping and wondered if anyone else has had these side effects? It could be a combination of infection and meds? Thank you for any replies.

[peege]

Its a pretty nasty bug so I'm sure the two antibiotics are essential. There are more than one strains of it.

Is it in your lungs? Perhaps you have acid reflux? I ask because these bacteria are normally in the gut and harmless. The following is from the British website Gov.uk

{ From:

UK Health Security Agency

Published

30 November 2017

Klebsiella species are a Gram-negative rod shaped bacteria belonging to the Enterobacteriaceae family. They are commonly found in the environment and in the human intestinal tract (where they do not normally cause disease).

These species can cause a range of healthcare-associated infections, including pneumonia, bloodstream infections, wound or surgical site infections and meningitis. Acquired endogenously (from the patient’s own gut flora) or exogenously from the healthcare environment.

Patient to patient spread occurs through contaminated hands of healthcare workers or less commonly by contamination of the environment. Vulnerable patients, like the immune compromised, are most at risk. Infections can be associated with use of invasive devices or medical procedures.

Treatment

Klebsiella spp. can become resistant to a wide range of antibiotics through a variety of mechanisms for example, production of Extended-Spectrum Beta-lactamases or carbapenemase.

Carbapenem resistance: management and prevention

Extended-spectrum beta-lactamases (ESBLs): treatment, prevention, surveillance

1 December 2013 Guidance

Prevention

Good hand hygiene practice in healthcare settings prevents the acquisition and spread of Klebsiella spp. Faecal contamination is how the bacteria is acquired and spread.

NICE antimicrobial stewardship guidance

World Health Organization 5 moments of hand hygiene }

Hand hygiene is very essential to stop the spread &/or re-infection

[PAP48 in reply to peege]

Thank you for the info Peege, yes it is in my lungs. I’m not aware I have acid reflux, I’ve had it before but this time it’s being very stubborn to get rid of. I’ve only been on the meds 1 week so hopefully by the end of the 4 weeks I’ll have seen the back of it!