365 Errors With MY DNA

Here is a run down on errors flagged with my DNA unforantly my cancer risk given MY gene coding is 46% also chronic inflation 50% and arthritis 60%.

But it's NOT all bad news as I carry gene that asprin reduces my cancer risk.

...................................................................................................

"Index","Name","Magnitude","Repute","Summary","Chrom","Pos","Gene","# Refs","Max Magnitude"

"0","rs351855(T;T)","3.2","Bad","2x increased prostate cancer risk; among breast cancer patients, herceptin is less effective","5","177093242","FGFR4","16","3.2"

"1","rs2395029(G;T)","3.2","Bad","HLA-B*5701 carrier","6","31464003","HCP5","32","4"

"2","gs122","3.1","Bad","7x risk of baldness","","","","",""

"3","rs3093726(C;T)","3.1","Bad","carrier. risk of toxicity from some medications","6","31579012","TNF","3","4"

"4","rs3815148(C;C)","3","Bad","1.34x increased risk of Osteoarthritis","7","107297975","COG5","2","3"

"5","rs4151667(A;T)","3","Bad","age related macular degeneration","6","31946247","CFB","18","3.1"

"6","rs910873(A;G)","3","Bad","1.7x increased risk of melanoma; increased risk of squamous cell carcinoma","20","34583968","PIGU","11","4"

"7","rs16969968(A;A)","3","Bad","higher risk for nicotine dependence, lower risk for cocaine dependence","15","78590583","CHRNA5","105","3"

"8","rs3903239(C;C)","3","Bad","higher frequency of atrial fibrillation","1","170600176","","2","3"

"9","rs1045642(T;T)","3","Bad","altered drug metabolism and bioavailability; moderately increased risk for certain cancers","7","87509329","ABCB1","109","3"

"10","rs2180439(T;T)","3","Bad","2x increased risk of Male Pattern Baldness.","20","21872462","","5","3"

"11","rs7754840(C;G)","3","Bad","1.3x increased risk for type-2 diabetes","6","20661019","CDKAL1","72","3"

"12","rs1333049(C;G)","3","Bad","1.5x increased risk for CAD","9","22125504","","98","4"

"13","rs13266634(C;C)","3","Bad","increased risk for type-2 diabetes","8","117172544","SLC30A8","121","3"

"14","rs2011077(G;G)","3","Bad","In Japanese, 6.2x increased risk of developing prostate cancer, a 3x increased risk of developing BPH, and a 5.5x increased risk of developing metastatic prostate cancer","5","177094455","FGFR4","1","3"

"15","i5005436(C;T)","3","Bad","miscalled by 23andMe, but should indicate being a carrier of allele for congenital adrenal hyperplasia","6","32008312","CYP21A2","","3"

"16","rs3095318(A;T)","3","Bad","In Japanese populations, associated with HLA-B*5801 allele and allopurinol side effects","6","31088145","CDSN","1","3"

"17","gs311","2.7","Bad","Slow metabolizer of DCA (a cancer drug, and a drug used in metabolic problems in children, substance found in chlorinated swimming pool water),slow metabolizer of protein","","","","",""

"18","rs6983267(G;T)","2.7","Bad","1.3x risk of prostate cancer; aspirin reduces risk of colorectal cancer","8","127401060","CCAT2","153","3.2"

"19","rs8034191(C;C)","2.6","Bad","1.80x lung cancer risk; decreased response to alcohol","15","78513681","AGPHD1","46","2.6"

"20","rs6265(A;G)","2.6","Bad","Increased risk of mental health disorders","11","27658369","BDNF","196","3"

"21","gs155","2.5","Bad","CYP3A5 non-expressor","","","","",""

"22","gs281","2.5","Bad","part of the 88% of the population claimed not to maintain weight loss unless you perform high energy exercise","","","","",""

"23","rs12536657(A;A)","2.5","Bad","hypermetropia risk - longsightedness","7","81720892","HGF","3","2.5"

"24","rs17782313(C;C)","2.5","Bad","adults likely to be 0.44 BMI units higher","18","60183864","MC4R","92","2.5"

"25","rs663048(T;T)","2.5","Bad","3x increased risk of developing lung cancer","22","26299111","SEZ6L","1","2.5"

"26","rs795484(A;A)","2.5","Bad","Even more increased morphine dose requirement and postoperative pain in tonsillectomy and adenoidectomy","12","118152057","TAOK3","2","2.5"

"27","rs6441286(G;G)","2.5","Bad","3.08x chance of developing primary biliary cirrhosis","3","160011091","IL12A-AS1","4","2.5"

"28","rs2073963(G;G)","2.5","Bad","increased risk of baldness","7","18838251","HDAC9","1","2.5"

"29","rs1051730(T;T)","2.5","Bad","1.8x increased risk of lung cancer; reduced response to alcohol, therefore possibly increased risk of alcohol abuse","15","78601997","CHRNA3","96","2.5"

"30","rs17487223(T;T)","2.5","Bad","1.28x lung cancer risk","15","78631645","CHRNB4","9","2.5"

"31","rs1799971(A;G)","2.5","Bad","stronger cravings for alcohol. if alcoholic, naltrexone treatment 2x more successful","6","154039662","OPRM1","36","2.6"

"32","rs2241880(C;C)","2.5","Bad","2x-3x increased risk for Crohn's disease in Caucasians","2","233274722","ATG16L1","30","2.5"

"33","rs10490924(G;T)","2.5","Bad","2.7x risk for age related macular degeneration","10","122454932","ARMS2","60","3.5"

"34","rs12340895(C;G)","2.5","Bad","Increased odds (2 fold?) of developing V617F-positive MPN","9","5076691","JAK2","3","3.5"

"35","rs10974944(C;G)","2.5","Bad","Increased odds (2 - 4 fold?) of V617F-associated MPNs","9","5070831","JAK2","12","3"

"36","rs3780374(A;G)","2.5","Bad","Substantially increased odds of developing V617F-positive MPN.","9","5099677","JAK2","","2.8"

"37","rs11672691(G;G)","2.5","Bad","1.39x increased risk for PCSM in patients with prostate cancer","19","41479679","SLC26A6","1","2.5"

"38","rs1421085(C;T)","2.5","Bad","~1.3x increased obesity risk","16","53767042","FTO","52","3.1"

"39","rs1121980(C;T)","2.5","Bad","1.67x risk for obesity","16","53775335","FTO","31","3"

"40","rs664143(C;T)","2.5","Bad","Higher risk for number of cancers","11","108354934","ATM","11","2.5"

"41","rs776746(G;G)","2.5","Bad","CYP3A5*3 homozygote; CYP3A5 non-expressor","7","99672916","CYP3A5","35","2.5"

"42","rs2274223(G;G)","2.4","Bad","1.9x increased risk for stomach & esophageal cancer (seen in Han Chinese)","10","94306584","PLCE1","28","2.4"

"43","rs9939609(A;T)","2.4","Bad","1.3x risk for T2D; obesity risk","16","53786615","FTO","306","3"

"44","rs1799990(A;A)","2.3","Bad","Increased chance of Prion Disease (PrP 129 Met homozygote)","20","4699605","PRNP","19","2.3"

"45","rs2305089(T;T)","2.2","Bad","higher risk for chordoma","6","166165782","T","3","2.2"

"46","rs2231137(G;G)","2.2","Bad","~1.5-3x increased risk for ischemic stroke","4","88139962","ABCG2","6","2.2"

"47","gs223","2.1","Bad","One copy of GCH1 variant associated with lower levels of tetrahydrobiopterin","","","","",""

"48","rs807701(C;C)","2.1","Bad","2-5x increased dyslexia risk","6","24273563","DCDC2","2","2.1"

"49","rs10871777(G;G)","2.1","Bad","adults likely to be 0.44 BMI units higher","18","60184530","MC4R","5","2.1"

"50","rs7080536(A;G)","2.1","Bad","~2x higher risk for carotid stenosis, venous thromboembolism","10","113588287","HABP2","3","3"

"51","rs6313(T;T)","2.1","Bad","depression, panic, stress response","13","46895805","HTR2A","56","2.1"

"52","rs2301436(A;A)","2.1","Bad","","6","167024500","FGFR1OP","11","2.1"

"53","rs17563(C;C)","2.1","Bad","Risk for otosclerosis","14","53950804","BMP4","12","2.1"

"54","rs10821936(C;T)","2.1","Bad","Higher risk of childhood acute lymphoblastic leukemia","10","61963818","ARID5B","14","2.5"

"55","rs944289(C;T)","2.1","Bad","1.3x increased thyroid cancer risk","14","36180040","","16","2.2"

"56","rs560887(G;G)","2.1","Bad","Avg. fasting Plasma Glucose 5.18 mmol/L (93 mg/dl).","2","169763148","G6PC2","39","2.1"

"57","rs1801131(A;C)","2.1","Bad","Possibly impaired folate metabolism","1","11794419","MTHFR","124","2.5"

"58","rs17070145(C;C)","2.1","Bad","reduced memory abilities","5","168418786","WWC1","16","2.1"

"59","rs2834167(A;A)","2.1","Bad","2.67x increased risk for systemic sclerosis","21","33268483","IL10RB","8","2.1"

"60","rs646776(A;A)","2.1","Bad","1.2x risk of coronary artery disease","1","109275908","CELSR2","39","2.1"

"61","rs3761847(A;G)","2.1","Bad","1.32 x risk of rheumatoid arthritis.","9","120927961","TRAF1","40","2.2"

"62","rs7837688(G;G)","2.1","Bad","1.7x increased risk for prostate cancer","8","127527115","","10","2.1"

"63","rs543749(G;G)","2.1","Bad","if a smoker, higher risk risk for COPD in somkers in a Hispanic population","20","3669032","ADAM33","5","2.1"

"64","rs5186(A;C)","2.1","Bad","~1.4x increased risk of hypertension","3","148742201","AGTR1","66","4"

"65","gs140","2","Bad","NAT2 slow metabolizer","","","","",""

"66","gs154","2","Bad","NAT2 Slow metabolizer","","","","",""

"67","rs12567232(A;A)","2","Bad","Increased risk for Crohn's Disease","1","67262335","","2","2"

"68","rs642961(A;A)","2","Bad","2.40x increased risk of cleft lip","1","209815925","","12","2"

"69","rs855913(G;T)","2","Bad","reduced survival with ALS","7","149506571","","1","2.1"

"70","rs4673(T;T)","2","Bad","3.9x increased risk for cerebral ischemia","16","88646828","CYBA","11","2"

"71","rs2201841(C;C)","2","Bad","1.5x increased risk for Crohn's disease","1","67228519","IL23R","37","2"

"72","rs16944(A;A)","2","Bad","Increased risk for osteoarthritis","2","112837290","IL1B","106","2"

"73","rs2156921(G;G)","2","Bad","1.29x increased risk for depression","22","23226876","BCR","1","2"

"74","rs1127354(A;C)","2","Bad","lower ITPA production; be aware if treated with ribavirin or mercaptopurine","20","3213196","ITPA","36","3.2"

"75","rs6601764(C;C)","2","Bad","1.52x increased risk of developing Crohn's disease","10","3820350","","","2"

"76","rs9642880(T;T)","2","Bad","1.5x increased bladder cancer risk","8","127705823","CASC11","15","2"

"77","rs1800896(A;A)","2","Bad","1.8x increased prostate cancer risk","1","206773552","IL10","125","2"

"78","rs2736990(C;C)","2","Bad","Increased risk of developing Parkinson's Disease","4","89757390","SNCA","6","2"

"79","rs7216389(T;T)","2","Bad","1.5x increased risk for Childhood Asthma.","17","39913696","GSDMB","27","2"

"80","rs1544410(A;A)","2","Bad","Increased risk of low bone mineral density disorders","12","47846052","VDR","134","2"

"81","rs1064395(A;G)","2","Bad","Having any copies of A at this SNP heightens your risk for bipolar disorder and schizophrenia.","19","19250926","NCAN","5","2.1"

"82","rs1799884(A;G)","2","Bad","1.3x increased risk for Type 2 Diabetes. Mothers have babies 27g heavier.","7","44189469","GCK","16","3"

"83","rs2143340(C;T)","2","Bad","increased risk of dyslexia and poor reading performance","6","24658843","TTRAP","7","2.3"

"84","rs3129934(C;T)","2","Bad","Increased risk of Multiple Sclerosis.","6","32368410","C6orf10","7","2.2"

"85","rs10811661(C;T)","2","Bad","1.2x increased risk for type-2 diabetes","9","22134095","","110","2.1"

"86","rs2230199(C;G)","2","Bad","1.6x+ risk of ARMD","19","6718376","C3","50","2"

"87","rs3135391(C;T)","2","Bad","HLA-DRB1*1501 carrier; higher multiple sclerosis risk","6","32443210","HLA-DRA","3","3"

"88","rs3819331(C;T)","2","Bad","increased risk of autism","11","112228687","PTS","","2"

"89","rs1160312(A;A)","2","Bad","1.6x increased risk of Male Pattern Baldness.","20","22069865","C19orf26","5","2"

"90","rs4027132(A;A)","2","Bad","1.51x increased risk of developing bipolar disorder","2","11897366","","2","2"

"91","rs201571(T;T)","2","Bad","more likely to go bald","20","22032876","","2","2"

"92","rs4961(G;T)","2","Bad","1.8x increased risk for high blood pressure","4","2904980","ADD1","13","2.1"

"93","rs2352028(C;T)","2","Bad","","13","91792975","GPC5","5","2"

"94","rs3212227(A;C)","2","Bad","Significantly increased risk of developing cervical cancer","5","159315942","IL12B","75","2"

"95","rs6997709(G;T)","2","Bad","1.2x higher risk for hypertension","8","139167781","","2","2"

"96","rs31489(C;C)","2","Bad","Increased risk for lung cancer and emphysema","5","1342599","CLPTM1L","9","2"

"97","rs25487(G;G)","2","Bad","2x higher risk for skin cancer; possibly other cancers","19","43551574","XRCC1","47","2"

"98","rs3775291(G;G)","2","Bad","common but higher risk of age related macular degeneration","4","186082920","TLR3","21","2.2"

"99","rs1050631(C;T)","2","Bad","Mean Survival Time of 25 months for esophageal squamous-cell carcinoma","18","36114157","SLC39A6","1","2.1"

"100","rs4129148(C;G)","2","Bad","3x risk of schizophrenia.","X","1029445","CSF2RA","5","2"

"101","rs1265181(C;G)","2","Bad","increased risk for psoriasis","6","31188008","","8","2.5"

"102","rs10984447(A;G)","2","Bad","1.17x increased risk for multiple sclerosis","9","119222275","DBC1","4","2"

"103","rs2987983(C;T)","2","Bad","1.2x increased risk of prostate cancer","14","64296935","ESR2","17","2"

"104","rs744373(C;T)","2","Bad","1.17x risk of Alzheimer's","2","127137039","","16","2"

"105","rs738409(C;G)","2","Bad","increased liver fat, odds of alcoholic liver disease","22","43928847","PNPLA3","114","3.1"

"106","rs11190870(C;T)","2","Bad","Possibly increased risk of scoliosis","10","101219450","","4","2.5"

"107","rs710521(A;A)","2","Bad","1.4x increased risk of developing bladder cancer.","3","189928144","","9","2"

"108","rs16942(A;G)","2","Bad","very slightly increased breast cancer risk","17","43091983","BRCA1","4","2"

"109","rs17696736(A;G)","2","Bad","1.34x risk of type-1 diabetes","12","112049014","NAA25","27","2.5"

"110","rs4911414(G;T)","2","Bad","2-4x higher risk of sun sensitivity if part of risk haplotype","20","34141638","","12","2"

"111","rs965513(A;G)","2","Bad","1.77x increased thyroid cancer risk","9","97793827","","26","2"

"112","rs2395185(G;T)","2","Bad","2.72x higher risk of Type 1 Diabetes, but 0.88x lower risk of Ulcerative Colitis.","6","32465390","","18","3"

"113","rs3184504(C;T)","2","Bad","increased risk for celiac disease","12","111446804","SH2B3","32","3"

"114","rs4633(C;T)","2","Bad","higher risk for endometrial cancer","22","19962712","COMT","52","2"

"115","rs3738919(A;C)","2","Bad","1.94x risk of developing rheumatoid arthritis","2","186656533","ITGAV","1","2.5"

"116","rs7961152(A;C)","2","Bad","1.2x higher risk for hypertension","12","24828677","BCAT1","3","2"

"117","rs5174(A;G)","2","Bad","1.3x increased risk for heart disease","1","53247055","LRP8","9","2"

"118","rs7807268(C;G)","2","Bad","1.3x risk for Crohn's disease","7","148560956","","","2"

"119","rs2073711(C;C)","2","Bad","Back Pain: normal (higher) risk of Lumbar Disc Disease.","15","65201874","CILP","2","2"

"120","rs1333048(A;C)","2","Bad","1.3x increased coronary artery disease risk","9","22125348","","6","2.1"

"121","rs10757278(A;G)","2","Bad","1.3x risk for Heart Attack. Normal risk for Abdominal Aortic Aneurysm and Brain Aneurysm.","9","22124478","","79","2.5"

"122","rs3923809(A;A)","2","Bad","1.9x risk for developing restless legs syndrome","6","38473194","BTBD9","9","2"

"123","rs1024611(C;T)","2","Bad","increased risk of exercise induced ischemia","17","34252769","CCL2","21","2.2"

"124","rs6457617(C;T)","2","Bad","2.3x risk of rheumatoid arthritis","6","32696074","","21","2.1"

"125","rs1015362(G;G)","2","Bad","2-4x higher risk of sun sensitivity if part of risk haplotype.","20","34150806","","11","2"

"126","rs2383207(A;G)","2","Bad","increased risk for heart disease","9","22115960","CDKN2BAS","32","2.1"

"127","rs1495741(A;A)","2","Bad","NAT2 slow metabolizer (predicted)","8","18415371","","14","2"

"128","rs326(A;A)","2","Bad","lower HDL cholesterol","8","19961928","LPL","8","2"

"129","rs1585215(A;G)","2","Bad","2x increased risk for Hodgkin lymphoma","4","102523317","NFKB1","1","2.1"

"130","rs2383206(A;G)","2","Bad","1.4x increased risk for heart disease","9","22115027","CDKN2BAS","31","3"

"131","rs1050152(C;T)","2","Bad","2.1x increased risk of Crohn's disease","5","132340627","SLC22A4","24","2.1"

"132","rs13153971(C;T)","2","Bad","Normal (higher) risk of Asthma.","5","150201758","SLC6A7","","2"

"133","rs6897932(C;C)","2","Bad","1.08x increased risk for multiple sclerosis","5","35874473","IL7R","54","2.1"

"134","rs800292(C;C)","2","Bad","5% higher risk of Age related macular degeneration","1","196673103","CFH","28","2"

"135","rs6908425(C;C)","2","Bad","1.95x increased risk of developing Crohn's disease","6","20728500","CDKAL1","13","2"

"136","rs27072(C;C)","2","Bad","2x risk of severe alcohol withdrawal. Possible increased odds of ADHD.","5","1394407","SLC6A3","7","2"

"137","rs7250581(G;G)","2","Bad","1.4x risk","19","29573489","","2","2"

"138","rs1385699(T;T)","2","Bad","increased risk of baldness","X","66605144","EDA2R","5","2"

"139","rs2032583(T;T)","2","Bad","7x less likely to respond to certain antidepressants.","7","87531245","ABCB1","11","2"

"140","rs2235040(G;G)","2","Bad","7x less likely to respond to certain antidepressants","7","87536434","ABCB1","3","2"

"141","rs2811712(A;A)","2","Bad","Normal (higher) risk of physical impairment with age.","9","21998036","CDKN2BAS","1","2.1"

"142","rs11200638(A;G)","2","Bad","~2x increased risk of age related macular degeneration","10","122461028","HTRA1","77","3.5"

"143","rs3025039(C;T)","2","Bad","2.6x increased risk for ARMD in a Taiwanese population","6","43784799","VEGFA","39","2"

"144","rs4444903(A;G)","2","Bad","3.5x risk of hep-cancer in cirrhosis patients; higher glioma risk","4","109912954","EGF","19","2.1"

"145","rs383830(A;A)","2","Bad","1.9x risk","5","100613278","","3","2"

"146","rs1734791(A;A)","2","Bad","1.4x increased risk for lupus","X","154065469","MECP2","","2"

"147","rs1858830(C;C)","2","Bad","2x risk of autism","7","116672385","MET","7","2"

"148","rs449647(A;A)","2","Bad","lower levels of ApoE","19","44905307","APOE","5","2"

"149","rs7923837(A;G)","1.9","Bad","1.6x risk for T2D","10","92722160","","35","2"

"150","rs402710(C;C)","1.9","Bad","Common, but higher lung cancer risk ?","5","1320607","CLPTM1L","26","1.9"

"151","rs4950928(C;C)","1.9","Bad","Normal (higher) risk of Asthma.","1","203186754","CHI3L1","25","2"

"152","rs3135388(C;T)","1.8","Bad","3x higher risk of multiple sclerosis","6","32445274","HLA-DRA","30","2"

"153","rs4474514(A;G)","1.8","Bad","3x increased testicular cancer risk for men","12","88560182","KITLG","4","1.8"

"154","rs6700125(C;T)","1.8","Bad","1.2x increased risk for ALS","1","59237125","","5","2"

"155","rs801114(G;T)","1.8","Bad","Normal (slightly higher) risk of Basal Cell Carcinoma.","1","228862088","","7","2.1"

"156","rs2278206(T;T)","1.8","Bad","1.16x increased risk for asthma","2","98555781","INPP4A","1","1.8"

"157","rs8055236(G;T)","1.7","Bad","1.9x risk for heart disease","16","83178793","CDH13","4","1.7"

"158","rs7192(G;T)","1.7","Bad","1.7x increased risk for developing a peanut allergy","6","32443869","HLA-DRA","11","3"

"159","rs9275596(C;T)","1.7","Bad","1.7x increased risk for developing a peanut allergy, 0.54x risk of IgA Nephropathy in Chinese","6","32713854","LOC100507686","2","3"

"160","rs4132601(G;T)","1.7","Bad","somewhat (1.7x) increased risk for acute lymphoblastic leukemia","7","50402906","IKZF1","6","2.4"

"161","rs2227692(T;T)","1.6","Bad","1.6x higher risk for diffuse gastric cancer","7","101135963","SERPINE1","2","1.6"

"162","rs1800450(A;A)","1.6","Bad","mannose binding deficiency but of low clinical importance","10","52771475","MBL2","11","1.6"

"163","rs2046210(T;T)","1.6","Bad","1.6x increased breast cancer risk in certain women","6","151627231","","37","1.6"

"164","rs11523871(C;C)","1.6","Bad",">1.6x increased breast cancer risk for women over 60","10","122570194","DMBT1","1","1.6"

"165","rs1800588(C;C)","1.6","Bad","normal HDL-C levels","15","58431476","LIPC","15","1.8"

"166","rs3764880(A;A)","1.6","Bad","1.2 - 1.8x increased tuberculosis risk","X","12906707","TLR8","2","1.6"

"167","rs2981745(T;T)","1.6","Bad",">1.6x increased risk for breast cancer in females over 60","10","122560678","DMBT1","2","1.6"

"168","gs186","1.5","Bad","HLA-B*5801‎‎ heterozygosity is possible, unfortunately this is just too common to be useful","","","","",""

"169","rs619203(C;G)","1.5","Bad","increases susceptibility to Myocardial Infarction 1.15 times","6","117301021","ROS1","3","1.5"

"170","rs10889677(A;A)","1.5","Bad","1.5x increased risk for certain autoimmune diseases","1","67259437","IL23R","42","2"

"171","rs10895068(A;G)","1.5","Bad","2.5x increased odds of breast cancer among hormone-using postmenopausal women","11","101129483","PGR","16","1.5"

"172","rs17319721(A;A)","1.5","Bad","reported to have some negative associations with kidney function","4","76447694","SHROOM3","6","1.5"

"173","rs1154155(G;T)","1.5","Bad","1.94x increased risk for narcolepsy","14","22533736","TRA","5","2.5"

"174","rs12210050(C;T)","1.5","Bad","Slightly higher risk for basal cell carcinoma","6","475489","","3","1.5"

"175","rs966221(C;C)","1.5","Bad","1.5x increased stroke risk certain populations","5","60206693","PDE4D","10","1.5"

"176","rs3125923(A;G)","1.5","Bad","slightly (50%) increased risk for Taxane-induced peripheral neuropathy","1","68392796","","1","2"

"177","rs401681(C;C)","1.5","Bad","~1.2x increased risk for several types of cancer","5","1321972","CLPTM1L","47","1.5"

"178","rs1994090(G;T)","1.5","Bad","Slightly increased risk of developing Parkinson's Disease","12","40034759","SLC2A13","3","2"

"179","rs309375(T;T)","1.5","Bad","Larger mosquito bites","4","122760001","","","1.5"

"180","rs358806(A;C)","1.5","Bad","0.86x increased risk of developing Type-2 diabetes","3","55279372","","2","2"

"181","rs13149290(C;T)","1.5","Bad","Slightly increased risk of developing prostate cancer","4","145829814","ZNF827","1","1.5"

"182","rs199533(C;T)","1.5","Bad","Slightly increased risk of developing Parkinson's Disease","17","46751565","NSF","2","2"

"183","rs10859871(A;C)","1.5","Bad","Slight (~1.2x) increase in endometriosis risk","12","95318100","","3","1.5"

"184","rs3814570(C;T)","1.5","Bad","1.3x increased risk for Crohn's disease with ileal involvement","10","112948751","TCF7L2","","1.5"

"185","rs6604026(C;T)","1.5","Bad","1.15x risk of multiple sclerosis","1","92838046","RPL5","7","2"

"186","rs700651(A;G)","1.5","Bad","~1.18x increased risk of aneurysm","2","197766990","BOLL","6","2"

"187","rs2007153(G;G)","1.5","Bad","increased risk of schizophrenia in limited study","9","133638697","DBH","","1.5"

"188","rs10993994(C;T)","1.5","Bad","increased prostate cancer risk (odds ratio 1.2)","10","46046326","MSMB","56","2"

"189","rs10883365(A;G)","1.5","Bad","1.2x increased risk for developing Crohn's disease","10","99528007","LINC01475","8","2"

"190","rs1169300(A;G)","1.5","Bad","~1.5x increased lung cancer risk","12","120993422","HNF1A","4","2"

"191","rs2464196(C;T)","1.5","Bad","~1.5x increased lung cancer risk","12","120997624","HNF1A","9","2"

"192","rs6498169(A;G)","1.5","Bad","1.14x risk of multiple sclerosis","16","11155472","CLEC16A","18","2"

"193","rs225014(C;T)","1.5","Bad","Hypothyroid patients might benefit from combination T4/T3 therapy (?)","14","80203237","DIO2","17","1.5"

"194","rs12037606(A;G)","1.5","Bad","1.22x risk of developing Crohn's disease","1","172929262","","","2"

"195","rs11171739(C;T)","1.5","Bad","1.34x risk of developing Type-1 diabetes","12","56076841","ERBB3","10","2"

"196","rs10260404(C;T)","1.5","Bad","1.20x risk of developing ALS","7","154513713","DPP6","10","2"

"197","rs144848(G;T)","1.5","Bad","very slightly increased breast cancer risk","13","32332592","BRCA2","18","2"

"198","rs7536563(A;G)","1.5","Bad","1.12x risk of multiple sclerosis","1","92883489","FAM69A","2","2"

"199","rs872071(A;G)","1.5","Bad","~1.5x increased risk for chronic lymphocytic leukemia","6","411064","IRF4","17","1.5"

"200","rs10757272(C;T)","1.5","Bad","1.30x increased risk for Coronary artery disease","9","22088261","CDKN2B-AS1","3","2"

"201","rs3087243(A;G)","1.5","Bad","increased risk for auto-immune diseases","2","203874196","CTLA4","83","1.5"

"202","rs13181(G;T)","1.5","Bad","1.12x increased risk for cutaneous melanoma","19","45351661","ERCC2","44","2"

"203","rs2280714(A;G)","1.5","Bad","1.4x increased risk of SLE","7","128954671","TNPO3","22","1.5"

"204","rs1861494(C;T)","1.5","Bad","IBD risk","12","68157629","IFNG","3","1.5"

"205","rs599839(A;A)","1.5","Bad","1.4x increased risk for heart disease","1","109279544","PSRC1","48","1.5"

"206","rs17221417(C;G)","1.5","Bad","1.3x higher risk for Crohn's disease","16","50705671","NOD2","1","2"

"207","rs4785763(A;C)","1.5","Bad","1.5x higher risk for melanoma","16","90000528","AFG3L1","1","1.5"

"208","rs2881766(T;T)","1.5","Bad","Slightly increased risk for pregnancy-induced hypertension","6","151797984","ESR1","5","1.5"

"209","rs420259(T;T)","1.5","Bad","Normal risk of Bipolar Disorder.","16","23622705","PALB2","5","1.9"

"210","rs501120(A;A)","1.5","Bad","common, but >1.3x increased risk for heart disease","10","44258419","","10","1.5"

"211","rs7341475(G;G)","1.5","Bad","1.58x increased schizophrenia risk for women","7","103764368","RELN","12","1.5"

"212","rs1012053(A;A)","1.5","Bad","Normal (higher) risk of Bipolar Disorder.","13","42079301","DGKH","7","2.1"

"213","rs1867277(A;G)","1.5","Bad","1.5x increased risk for thyroid cancer","9","97853632","FOXE1","7","2"

"214","rs2272127(C;C)","1.5","Bad","Associated with herpes and schizophrenia","2","102423413","IL18RAP","1","1.5"

"215","rs10865331(A;A)","1.4","Bad","1.4x higher risk for ankylosing spondylitis","2","62324337","","8","1.4"

"216","rs498872(T;T)","1.4","Bad","1.4x higher risk for glioma development","11","118606652","PHLDB1","17","1.4"

"217","rs1545843(A;A)","1.4","Bad","1.4x increased risk for depression (for those under 55)","12","84170289","","1","1.4"

"218","rs7025486(A;G)","1.4","Bad","slight (1.2x) increase in risk for abdominal aortic aneurysm and some vascular disorders","9","121660124","DAB2IP","2","1.6"

"219","rs1805127(A;G)","1.4","Bad","slight (1.4x) increase in risk for atrial fibrillation","21","34449523","KCNE1","16","1.4"

"220","rs1126497(C;T)","1.4","Bad","1.4x increased risk for breast cancer","2","47373967","EPCAM","3","1.4"

"221","rs6010620(G;G)","1.4","Bad","1.4x higher risk for glioma development; but this is the common allele. 1.4x higher risk for atopic dermatitis in Han Chinese","20","63678486","RTEL1","32","1.4"

"222","rs3131296(G;G)","1.4","Bad","1.4x increased risk for schizophrenia","6","32205216","NOTCH4","7","1.4"

"223","rs17465637(C;C)","1.34","Bad","1.34x higher risk for myocardial infarction","1","222650187","MIA3","18","1.34"

"224","rs34330(T;T)","1.3","Bad","1.2x higher breast cancer risk; 1.3x higher risk for endometrial cancer (in Chinese women)","12","12717761","CDKN1B","13","1.3"

"225","rs4958847(A;G)","1.3","Bad","1.3x increased risk for Crohn's disease","5","150860025","IRGM","9","2.6"

"226","rs1375144(C;T)","1.3","Bad","1.32x increased risk of developing bipolar disorder (one study)","2","115483610","DPP10","1","1.5"

"227","rs2024513(A;G)","1.3","Bad","1.3x higher risk for schizophrenia (among Han Chinese)","2","50924881","NRXN1","","1.7"

"228","rs110419(A;G)","1.3","Bad","1.3x increased risk for neuroblastoma","11","8231306","LMO1","2","2.6"

"229","rs356219(A;G)","1.3","Bad","1.3x increased risk for Parkinson's disease","4","89716450","SNCA","15","1.6"

"230","rs2736100(G;T)","1.3","Bad","1.3x higher risk for glioma development, 2.1x risk of pulmonary fibrosis","5","1286401","TERT","69","2"

"231","rs10947262(C;C)","1.3","Bad","1.3x increased risk for osteoarthritis","6","32405535","BTNL2","1","1.3"

"232","rs1047286(C;T)","1.3","Bad","1.3x increased risk for age-related macular degeneration","19","6713251","C3","13","1.7"

"233","rs13387042(A;A)","1.25","Bad","1.24x increased risk for breast cancer","2","217041109","","41","1.25"

"234","rs2236225(C;T)","1.25","Bad","Possible increased risk of birth defects","14","64442127","MTHFD1","10","1.5"

"235","rs2814707(A;G)","1.2","Bad","1.2x increased risk for ALS","9","27536399","LOC102724192","6","1.2"

"236","rs3849942(A;G)","1.2","Bad","1.2x increased risk for ALS","9","27543283","","8","1.4"

"237","rs5370(G;T)","1.2","Bad","possibly lower HDL cholesterol in women","6","12296022","EDN1","16","1.2"

"238","rs393152(A;G)","1.2","Bad","Slight increased risk of both PD and AD","17","45641777","C17orf69","7","1.5"

"239","rs2252586(A;G)","1.2","Bad","1.2x higher risk for glioma development","7","54911231","","4","1.4"

"240","rs2072590(G;T)","1.2","Bad","1.2x increased risk for ovarian cancer","2","176177905","LOC401022","5","1.4"

"241","rs4977756(A;G)","1.2","Bad","1.39x higher risk for glioma development","9","22068653","CDKN2BAS","17","1.4"

"242","rs2076295(G;T)","1.2","Bad","One copy of the risk allele (G), slightly increased risk for pulmonary fibrosis","6","7562999","DSP","1","1.5"

"243","rs8050136(A;C)","1.2","Bad","1.2x increased risk for T2D in some populations","16","53782363","FTO","120","1.4"

"244","rs2223841(A;A)","1.2","Bad","more likely to go bald before age 40","X","67350329","","","2.1"

"245","rs6625163(A;A)","1.2","Bad","increased risk of baldness","X","67291142","","2","1.2"

"246","rs6036025(G;G)","1.2","Bad","more likely to go bald","20","22059230","C19orf26","","1.2"

"247","rs3802842(A;C)","1.17","Bad","1.17x increased risk of colorectal cancer","11","111300984","C11orf93","31","2"

"248","rs6812193(C;C)","1.1","Bad","slightly higher risk of developing Parkinson's Disease for caucasians","4","76277833","FAM47E","7","1.5"

"249","rs4324715(C;T)","1.1","Bad","1.5x increased testicular cancer risk for men","5","142289942","","2","1.2"

"250","rs688034(C;T)","1.1","Bad","1.1x risk higher risk for coronary artery disease","22","26293669","SEZ6L","4","2"

"251","rs2651899(A;G)","1.1","Bad","1.1x higher risk for migraines","1","3167148","PRDM16","7","1.2"

"252","rs1799966(A;G)","1.1","Bad","very slightly increased breast cancer risk","17","43071077","BRCA1","2","2"

"253","rs6897876(C;T)","1.1","Bad","slight increase in testicular cancer risk for men","5","142308074","","","1.2"

"254","rs4977574(A;G)","1.1","Bad","Some studies - but not others - report a slightly increased risk for myocardial infarction","9","22098575","CDKN2B-AS1","28","1.5"

"255","rs3758549(C;C)","1.1","Bad","increased risk of parkinson's disease","10","102244438","GBF1","11","1.1"

"256","rs2653349(G;G)","1.1","Bad","2-6x increased risk for cluster headaches","6","55277539","HCRTR2","4","1.1"

"257","rs925391(C;C)","1.1","Bad","more likely to go bald; common","X","67120595","","","3"

"258","rs11209026(G;G)","1.1","Bad","Normal, but higher risk for certain autoimmune diseases.","1","67240275","IL23R","103","3"

"259","rs1799913(C;C)","1.1","Bad","Hispanics may be at increased risk of heroin addiction.","11","18025708","TPH1","3","1.1"

"260","rs34516635(G;G)","1.1","Bad","Less longevity for Ashkenazi Jewish women.","15","98908747","IGF1R","1","1.5"

"261","rs7412(C;C)","1.1","Bad","more likely to gain weight if taking olanzapine","19","44908822","APOE","35","1.1"

"262","rs2291834(C;C)","1.07","Bad","very slightly higher risk for myocardial infarction","1","222658953","MIA3","1","1.07"

"263","rs1805762(C;G)","Â ","Bad","1.23x risk for hypertension","12","8945306","M6PR","1",""

"264","rs12304921(G;G)","Â ","Bad","1.9x risk type 2 diabetes","12","50963759","HIGD1C","2",""

"265","rs2273697(A;A)","1","Bad","Adverse reaction more likely to carbamazepine in epileptic patients","10","99804058","ABCC2","18","1"

"266","rs3760511(C;C)","Â ","Bad","1.16x increased risk for prostate cancer","17","37746322","HNF1B","4","1.2"

"267","rs11805303(T;T)","Â ","Bad","1.8x risk of Crohn's disease","1","67209833","IL23R","11",""

"268","rs11209032(A;A)","Â ","Bad","1.3x higher risk for spondylitis","1","67274409","IL23R","29",""

"269","rs1144393(C;C)","Â ","Bad","1.3x risk of chronic kidney disease in Japanese","11","102798678","MMP1","2",""

"270","rs6314(C;T)","Â ","Bad","higher risk for RA; better response to paroxetine as treatment for depression","13","46834899","HTR2A","20",""

"271","rs11974297(G;G)","1","Bad","Migraine","7","50550562","DDC","1","1"

"272","rs11881940(A;T)","Â ","Bad","1.9x risk of MI","19","41302527","HNRNPUL1","4",""

"273","rs2227928(C;C)","Â ","Bad","poorer response to pancreatic cancer combined treatment","3","142562770","ATR","3",""

"274","rs7027989(A;A)","Â ","Bad","1.26x increased myocardial infarction risk","9","21817755","MTAP","2",""

"275","rs5326(A;G)","1","bad","possible psychiatric risks","5","175443193","DRD1","10","1"

"276","rs12587781(G;T)","Â ","Bad","1.79x increased risk for narcolepsy in Europeans and 1.34x in Asians","14","22530666","TRA@","2",""

"277","rs9465871(C;T)","Â ","Bad","1.2x risk type-2 diabetes","6","20717024","CDKAL1","4",""

"278","rs1800437(C;G)","Â ","Bad","0.72x risk for heart disease","19","45678134","GIPR","6",""

"279","rs2269475(A;G)","Â ","Bad","increased rheumatoid arthritis risk","6","31616154","AIF1","2","1.8"

"280","rs2538976(G;G)","Â ","Bad","higher risk for speech development delay and/or impairment","7","147888727","CNTNAP2","1",""

"281","rs10958409(A;G)","Â ","Bad","1.37x increased aneurysm risk","8","54414531","","7",""

"282","rs2710102(C;C)","Â ","Bad","higher risk of speech development delay and/or impairment","7","147877298","CNTNAP2","8","2"

"283","rs10210302(T;T)","Â ","Bad","1.8x risk","2",

[Hidden]

The right about speech as I did have stammer ALSO my vitamin D

Think the more right than wrong AS I have good head of hair If only had to worry about baldness.

But all leave that to my brother

[Hidden in reply to Hidden]

hello jeff the report above seems to repeat its self of ur risk of deseases are these different strands of ur dna.forgot to say those nurses that help u do a great job and nobodys heard of them.

ive got vit m d difficency too have to have injection I was reading the other day vit d defficency can cause asthma .

hope u r having a good nights sleep.helen

[Hidden in reply to Hidden]

Hi Yer it seems like it's repeated as we have others but it's not ... I had to check that too.

This relates to picture .. genoset.com/index.php/Rs123...

I seem to have issues with brac1,2 -bap1 - jak1,2 - doc2b - tp53 one them is antibody THINK it's tp53 and doc2b have somthing to do with chronic inflamation and cancers.

But I will be seeing my doctors about my Jak Brac issues.

As to admiral nurses there is 85 for all of uk I think but think that was befour NHS Social Services took them on

[jackdup in reply to Hidden]

Do you know the name of the drug that is injected for Vitamin D deficiency? I have looked for an injectable form of Vitamin D but am told there is no such thing so would appreciate knowing what you have been getting.

Thank you

[Hidden in reply to jackdup]

I'm sorry to have mislead first of all iwas prescribed callceous with the right amount of vitamin d calcium is also included in them,was told to stop themcos I was allergic so dr gave me shot of vit d in bum few months later dr told me to take vitamin d tablets but he was no longer allowed to prescribe vit d recommended well know high street chain to buy them sorry to mislead you helen.

[jackdup in reply to Hidden]

No problem, thank you.

[sassy59]

Thinking of you JAS and that is s very detailed report there. Xxxxxx

[velvet55]

Hi Jeff

That seems to cover most things that you could possibly have an increased risk of.

Does that mean you will now be tea total and sugar free.

From what l can gather, you are not going bald, you are not obese, you will not get ovarian cancer, you are not schizophrenic.

Many of the risks are very low...thankfully.

Good luck with your new information, l know for you, it's good you have this profile about yourself.

For me personally, it would make me neurotic.

The only thing l would like to have is better screening, when you have a close relative, who had a terminal illness.

My mum died of ovarian cancer....the silent killer, as often you have no symptoms...it was discovered , sadly to late for my Mum.

This puts me and my sister of an increased risk of developing this illness.

Although not a definitive diagnosis, a simple blood test for a raised Ca125 level each year, can be an indication you are in an early, often treatable stage.

This wasn't offered routinely to me or my sister, l have to ask my GP annually to give me this test....my sisters GP will not give her the test.

All the best Jeff

xx

[JP1954 in reply to velvet55]

Agree with you there Velvet 55. Husband asked for another prostrate check including psa (he had the last one three years ago)He knows that this cannot be classified as screening because of the misleading psa results can give and GP's don't offer this practise due to this reason, but if psa increase is a cause for concern I gather that a urine test, after DRE, can pick up cancer cells. This was the £10 check everyone was excited about a few years ago - it is only performed privately.

Can your sister arrange for the ca 125 blood test privately or do you again need your GP's consent?

Regards JP

[velvet55 in reply to JP1954]

Hi JP

If my sister was a little more insistent with her GP , they would probably do it, but she has chosen to take his advice, that in his opinion your Ca125 test does not indicate it one way or the other....I chose otherwise, and on my GPs advice, have it done annually.

I think normal levels are below 35, my mums was 125 when she was diagnosed.

It costs me nothing,... our GP also knows about Mr V's dad dying of prostate cancer. and gives my husband annual testing, blood, urine and a physical examination....again, he has never charged him.

I know, the earlier these awful illnesses are found, the better chance of survival.

I would quite willingly pay a charge for this screening.

x

[JP1954 in reply to velvet55]

you are right, you need to be very insistent on having standard tests now, even if family history states that these should occur. I found that even getting a standard letter to go "private" for tests is jumping through hoops. I am glad you have an understanding GP, hold on to him/her.

Stay safe

Regards JP

[Tee1008]

All those pages nearly drained my ipad and my brain!! Are they helping you, Daz....? xxx

[JP1954]

dear Jeff. So what you are saying is that your normal.

Hubby has factor xi deficiency that's approx 1 in 1m I gather and he is the only one in his family. His mother died of breast cancer at 55 and his sister died at 80 with ovarian cancer. In fact over the last 5 years he has lost 5 siblings, all but one (parkinsons) to cancer. All smoked.

He also had gene mapping done at addensbrooks just for the fact that they wanted to study his genetic past, but did not want the results you wanted. Because what can you do. I read in a study that we all have latent cancer and it is kept in check by your ammune system. That's why you shouldn't smoke, but eat healthily, take regular exercise, including swimming and try not to stress. We are not going to live forever, not any of us. But to accept that and then to move on seems the biggest problem we all have.

I am like velvet55. Yes get regular tests but please don't dwell over what "may be" . I am one of the 6% with O- blood and my husband has A- blood and is only 6% of the population. Have your regular tests but please don't stress.

Regards JP

[Nanaeal]

Wow Jeff, I pleased you got the help you wanted to interpret your DNA results. Are you truly sure it's helpful. In the case of illness or disease which can be screened for & enable early detection diagnosis & treatment yes but otherwise isn't it just a worry. Why spoil Wednesday by worrying what may happen on Thursday??!!