Can I combine Vitamin K2 and Edoxaban (Lixiana)? (Dr. Stephen Sinatra)

[ZodiacLeo]

Hi. I'm 45 y old male that got diagnosed with persistent Afib back in beginning of November.

I have been reading a book by Dr. Stephen Sinatra (Reverse Heart Disease Now)

He was known as a doctor who was sick of seing the same patients return to hospital again and again. He called it revolving door syndrom or something, don't remember. That was because the patients were prescribed with "medications" that only worked on the symptoms and not the root cause.

He thought, why not combine the forces from the different fields? Different patients that was nearly doomed he managed to fix with this approach. Afib is a different story though, and quite difficult to fix without electro cardioversion or ablation and other stuff. (Sorry, English is not my native) Even electro cardioversion and ablation is not a guarantee for it to be fixed, I understood.

My symptoms can variate in strength, but it's important to make enough of the ATP energy in order for the heart to supply the other organs with sufficient oxygen. To get enough of that I combine CoQ10 with D-Ribose, L-Carnitine and Magnesium. Vitamine E and C are important, also vitamin b supplements according to the late Stephen Sinatra.

This was a little digression from the headline/topic but have anyone had any experience with combining Lixiana (Edoxaban) with vitamin K2? Does K2 prevent edoxaban to work? I know that warfarin is a "no go" with vitamin K2, but it has come to my understanding that this is not the case with Edoxaban.. Anyone with experience that care to elaborate?

All the best

[Autumn_Leaves]

To my knowledge, vitamin K2 supplements should be safe.

With older anticoagulants like warfarin the dietary advice is to eat a consistent amount of green leafy vegetables and other foods containing vitamin K1 rather than eating a lot one day and none the next. With newer anticoagulants this does not seem to be a problem, so you should be OK.

Vitamins K1 and K2 seem to be quite different and there isn’t much information on K2 in regard to its impact on blood clotting times. The concern is with K1 intakes from the diet and the older types of anticoagulant.

[jeanjeannie50 in reply to Autumn_Leaves]

I take vitamin K2 alongside Warfarin daily and have my own machine to check my INR. It's usually spot on what it should be. I do get a little fed up with people putting Warfarin (Coumadin down). A lot of members here choose to take it.

[ZodiacLeo in reply to jeanjeannie50]

Nice to see that people can take K2 together with warfarin.

[Autumn_Leaves in reply to jeanjeannie50]

Nothing wrong with taking warfarin. The warnings only apply to inconsistent dietary intake of K1 from leafy greens etc. These warnings don’t seem to apply to K2 intakes. It appears that K1 and K2 are quite different, even if they are both “vitamin K”.

[ZodiacLeo in reply to Autumn_Leaves]

Yes, I see. I suspected that it was ok since I have yet to find articles that says otherwise.

K2 is very important when taking anti coagulants I guess? Maybe more important with Warfarin since Warfarin blocks the K2 reseptors or something..Then you'll have the calsium build up in the soft tissues.. Meanwhile it is important to not have the blood to coagulate when taking anti coagulants, hehe. A little catch 22 there.

[Autumn_Leaves in reply to ZodiacLeo]

I don’t think you’ve anything to worry about.

These warnings only apply to vitamin K1 (NOT vitamin K2) and only for people on warfarin who don’t need to worry about K2 either. I know it’s confusing!

[Auriculaire in reply to Autumn_Leaves]

I did some ferretting on this a few weeks ago when this topic came up and came across some research into K2 and Warfarin. I can't remember the details and unfortunately did not bookmark it but the gist was that K2 and Warfarin do interact. But that it was important to have sufficient K2 as taking Warfarin has been correlated with artery calcification . Like Jean there are others here who take K2 supplements alongside their Warfarin and say that it actually helps to iron out fluctuations in INR.

[Autumn_Leaves in reply to Auriculaire]

That’s good to know.

[secondtry in reply to Autumn_Leaves]

That's what I read also.

[BobD Volunteer]

Edoxaban works on a different part of the clotting process to warfarin (a Vit K antagonist) so should be safe but please check with your pharmacist.

[ZodiacLeo in reply to BobD]

Yeah, I'll maybe do a double check. I want to take it in order to "guide" the calcium to the bones and teeth instead of the soft tissues, but maybe one doesn't need K2 supplements (other then we get from food) if Edoxaban doesn't interfere with the K2 reseptors in the body?🧐

[C66t in reply to ZodiacLeo]

I don't know re k2 but please check re vit e as well as it "thins :the blood.

[Gladstone001]

depending on what type of Vit K2 you are using, it can cause palpitations. I experimented with a K2 oral spray and it gave me AF after approx 2 weeks of use. If you search the web for K2 and palpitations or arrhythmia you will find lots of references.

[Ppiman]

I have read that the newer "DOAC" anticoagulants do not interact with any foods or supplements in the way that warfarin does. As for the book and the other stuff - well, there are many ways to try to make a living. Books, Amazon and the internet now provide a wonderful opportunity for far more people with less interest in science and honesty than they ought to have to have a stab at getting rich!

Steve

[Autumn_Leaves in reply to Ppiman]

Yes, it’s a shame that the “science fiction” category is already taken 😄

[dunestar]

I take Edoxaban for my paroxysmal A Fib. I've just started taking liposomal Vitamins A, D3, E and K2 mainly for the Vitamin D. I am reassured that the level of K2 at 45mcg is less than an egg.

[C66t in reply to dunestar]

Is vit e ok? I thought it "thins" the blood

[dunestar in reply to C66t]

Thanks. It's all mixed together. Only small amount 12 mg of Vit E but will look for product without it when I finish this lot. I'm taking it mainly for the Vit D.

[Auriculaire]

I take Apixaban and K2.

[MarkS]

I have taken K2 and warfarin for the last 12 years and had excellent stability of INR.

[C66t]

You might check vit e though. Im not sure it is ok with anticoagulants.

[ZodiacLeo]

Thanks for all the answers. I want to try Nattokinase aswell but not while I'm on Lixiana.. Any experiences?

[ZodiacLeo]

I'm on 60 mg lixiana one time a day (or night if you want). I have ordered Nattokinase because I suspect that all the anticoagulants will give you problems in the long run making the arteries calcified. Since Nattokinase also makes blood more anticoagulant I guess taking Edoxaban (Lixiana) at the same time, could be dangerous even though Nattokinase apparently doesn't "thin" the blood as much as Edoxaban.

So, my thought is to take HALF the dosage of Edoxaban (Lixiana) 30 mg at night and take the Nattokinase at daytime, approx 12 hours after the 30 mg of Edoxaban. I guess in theory that would be safe...? 🧐I don't know how many mg or FU of Nattokinase you have to take to make it dissolve plaque and clots, but I've heard around 4000-5000 FU a day should do the work. Anyone who knows?

Nattokinase also start dissolving clots pretty fast after only 4-6 hours, according to different articles, not me. That gives me a window of 6-8 hours for the Nattokinase to work and be absorbed (?) by the body before taking my 30 mg's Edoxaban at nighttime.. Anyone who's done anything similar?😬 Only asking because the doctors doesn't know any of this and they are biased and indoctrinated by the compendium made by big pharma.

IF one have blood clots you don't know about and takes nattokinase, can that clot in theory dislodge and travel to the brain, heart or lungs or will it shrink so it doesn't get stuck in the big arteries only in the smaller ones?

As you may see I been doing a lot of thinking here😂 and I would be very grateful if anyone has some answers👍

Have a great day!