Hi all I’m Scrump and new to this. At 64 and had heart attack and two strokes. Now have PAF and taking Apixaban plus the usual array of drugs . Just started taking mag citrate 300mg a day. My question is does anybody know if mag can change absorbanc of Apixaban or other drugs.
Magnesium citrate: Hi all I’m Scrump... - Atrial Fibrillati...
Magnesium citrate
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BobDVolunteer
Shouldn't be as most of us take it. Welcome to the club by the way.
Hi BobD can i just ask if you should be put on anticoagulant drugs to reduce risk of stroke surely the cardiologist and the team who did the ablation would assess you on this?
Sorry not sure I understand the question. Anticoagulation is essential before ablation, usually for three months and then probably similar afterwards even if your CHADSVASC score is zero. If your score is higher than zero and especially if it is two or above then for life is normal. Ablation doesn't remove stroke risk. Stroke prevention by anticoagulation should be the first thing considered for anybody presenting with AF. UK is not always good in this respect and there are many serious strokes that could be avoided if more was done to find and anticoagulate people with AF.
Thanks for this Bobd basically I was trying to say that I have had my ablation but just doing my research on stroke risk with AF and I have a score of 1 which according to the site I should consider being in blood thinners but no one GP or hospital told me this
Your choice if your score really is one . I am very risk averse and will never stop my anti coag.
Thanks for this Bobd I only scored one as I had hypertension in the past but BP is fine now
you can't remove any score once given.
So would hypertension in the past count as 1 point even though I don’t have any now? And if so would you think it’s worth going back to my GP for a review to go on anticoagulant drugs?
My EP recommended anticoagulation for life because of high BP in the past, even though it’s perfect now.
When I gave birth to my first child my BP was at a dangerously high level - so high they wouldn’t even move me from the delivery suite bed for 12 hours. I also had high blood pressure with my second pregnancy (I had preeclampsia with both) then it was perfect again for years.
Over the past couple of years with my arrhythmias it has fluctuated between high and low. I guess history can be repeated and the body has demonstrated a propensity to act in a certain way when under pressure so with the increased stroke risk with AF it’s better to be safe than sorry (as long as you don’t have a high bleeding risk).
Does your BP stay normal now? But of a frustrating one no one told me this before e.g GP or EP
Yes, it’s been good for a while now. I have a BP machine at home. Last night it was 112/77. I guess that’s why we need to do our own research and ensure we are empowered to ask questions of the doctors. We need to take responsibility for our own health and make sure our medical management is a partnership not a dictatorship (just doing what the doctor says without understanding why).
Wow 112/77 is good mine at best is 137/77 I’ve got a GP appointment next week so will discuss than thanks Kaz747
And is there certain foods you can eat because of anticoagulant drugs?
Can I ask you Jaz what your trick was to get your BP down. Mine is better now than it was, but still on Ramipril and Indapomide . ACE inhibitor and diuretic .
My last ablation has finally calmed my heart down (most of the time). I’ve always eaten fairly well but over the last year or so I’ve been more strict about what I eat (added lots more nuts & seeds & reduces processed carbs & red meat & monitored my micronutrients- protein, carbs, fat, sugar, fibre). I’ve also been stricter with my exercise and focused on sleep and stress reduction. I not on any BP drugs, just 1/2 beta blocker per day (25mg) which probably helps my BP as well as my arrhythmias.
That's brilliant. I am trying most of those diet moves too, though more red meat than I'd like, cos my iron levels are borderline. Were u on BP meds before the ablation ?
No but I was on them for a couple of years up until about 12 months ago. I injured my ankle in 2015 and then had reconstruction surgery in 2016 (spent 3 months in a wheelchair). That’s when my blood pressure and arrhythmia problems started. My EP thinks there was too much physical stress on my body, not to mention the emotional stress that comes with a bad injury.
How high was your BP after the birth ?
I can’t recall exactly- It was something like 250/150. I had to “sleep” on the delivery bed with a drip in one arm and a blood pressure cuff on the other arm with a nurse checking it every 15 minutes. I’d been on bed rest in hospital for 2 weeks & my baby was delivered at 35 weeks. She was in a humidcrib in the nursery and for the first three days I could only visit her in a wheelchair. My doctor said if it had been a few years earlier or I didn’t have first class medical care, one or both of us could have died.
In my second pregnancy my BP was fine then suddenly skyrocketed at 36 weeks so I was admitted to hospital and induced as they didn’t want to take any risks.
My doctor advised against any more pregnancies. I took his advice. He also said I may develop blood pressure problems later in life. Research I’ve done over the past couple of years also links preeclampsia with heart problems down the track but I’m not sure they knew that 28 years ago.
You have had such a traumatic life! Just hoping that everything continues to calm down.
I know - in between these dramas I’ve had a wonderful life so I’ll continue to focus on the positives 😃
Also I never even heard of anticoagulant drugs or risk factors to AF until after my ablation the EP that carried out my ablation didn’t mention anything and just told me it’s a beginin condition so frustrating
• in reply toBobD
Hi Bob
At my review I was given the option to come off apixaban by my EP as previously score of one for high BP resolved through lifestyle changes as did my LVH. I assumed same as you until he told me this. I refused and opted to stay on it.
Andy
Never heard of coags for 3 months b4 ablation . Are you sure ?
I always had. How else do they know there are no clots formed and waiting ? TOE before to check yes but a waste of time if they find one. I have always had to provide at least a month of INR readings above 2.5 even last month when I had my latest.
Only 2 contraindications that I know about for Mg are if you have kidney problems or if you have Myasthenia. Just be aware that for some people on drugs to lower BP it can heighten their affect.
This site gives the best info I have come across
ancient-minerals.com/magnes...
Nothing about anti-coagulants.
To add a little perspective,, 300mg is not alot of magnesium
Mag citrate is a nice clean form of magnesium and a bit more bio-available than the comon oxide or sulphate which just go through you. Assuming that you possibly absorb 40% of the auctual mineral you may be getting nearly as much as would be in a cup of spinich or a bit of fish.
If your worried that magnesium will block the uptake of the med this would only be a problem if the two were taken together.
To me it's a non issue but the easy solution if you have concerns,, take at septerate times!
Best Wishes, Ray
I think the only thing to avoid when taking apixaban is grapefruit and grapefruit juice
rxlist.com/magnesium/supple...
Worth a read? I suspect if magnesium causes very severe diarrhoea this may affect drug absorption but this would only be a problem with very high doses
A nice clean form of magnesium and not taken in access should not give one a loose stool.
For anyone using oral Magnesium Sulphate (epsom salts) as a source of magnesium,,, well this it the one that will go through you quickest,, it's also the cheapest.
Magnesium Oxide is the next one on the list,, perhaps a little more bioavailable but will still quickly give one a loose stool if enough it taken. Basicaly it is the body trying to get rid of the excess.
Magnesium Citrate is much more bioavailable theirfore a soft stool is much less likely.
300mg is a very low dose.
I auctualy take 2 Gms of mag cit three times daily,,, that's 6000 mgs a day without issue.
If you really want shocked thats 6000000 micrograms a day
Strange how big numbers alarm people but it's still only 6 gms.
I take it on advice if GP. Wards odd constipation and replenishes magnesium levels depleted by Dexilant - a proton pump inhibitor prescribed by allergist. Long story.
I stopped alcohol after April ablation and will be asking about weaning off the dexilant. But that’s another topic.
I like the magnesium citrate - take it dissolved with in my old pint glass.
I meant to say take it with water...
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