Hi,
I know PSA can rise during chemo initially but we are 7 treatments in and my dad’s PSA rises with each treatment. His latest scan showed some Mets are smaller in size and not lighting up as much. His MO says he’s not concerned about the PSA, but it’s the highest it’s ever been. Has anyone dealt with this before?
Can you please share the PSA levels including at start of treatment.
When he started his PSA was 8, then it jumped to the 30s for a few months and now it’s at 60. His last scan showed stable/improvement.
Scan is important if Scan showing stable and improvement, I would do scan every 4 week (CT scan and Bone Scan). I had similar situations
What happened in your situation similar to this?
I was in clinical trials call "ARX517" After 5 dosage. I stopped the treatment because of kidney functions. My PSA start raise from 2.15 once I stopped the treatment and now it is 12.65 during 6 month. I did scan every 4 week to check stability and improvement. In last scan We found new METS so now we are searching other treatment options.
Dr was clear that PSA is important for sure but when SCAN is stable in that case we focus on SCAN
When his psa increased last month he had the scan and it’s showing improvement. Now the psa has gone up again. He has another scan scheduled. It’s just confusing.
For me I’d be more focused on the scan results than the PSA number.
Yes agree
Watch the Mets and not so much the PSA as bouncing is common.
I guess I don’t get the rise in PSA while doing Chemo. Mine went down and was undetectable prior to round 5 and has been since. What type of chemo is he doing?
He is on Docetaxel
hi my PSA went down virtually with each lot of Chemo 5 lots in total at the end of which it was 0.1
A total success for me and after 5 years since receiving my first Chemo I’m still here and PSA is still 0.1 hope it goes ok for your dad
Thank you. I’m glad you’re doing well five years out from chemo! Success!
Of course you're concerned but I've seen tons of posts here where PSA goes up and then down... Remember that saying "what goes up must come down".... Give your Father our fondest regards (and to you and the rest of the family). Get ready for Christmas and make it a wonderful one for all!!!
p.s. Buy your Dad something he likes for Christmas since he already has something to love, that's YOU.
Good Luck, Good Health and Good Humor.
j-o-h-n
J-o-h-n you always have the best responses. Thank you! Happy holidays to you and yours!
I did not have chemo during my prostate treatment, only the 35 radiotherapy sessions so v sorry but cannot help. Best wishes to you both, cancer and the treatments are horrible things.
Chemo may only work for a short duration. He will need a break. There are other paths.
There are other paths grasshopper. None better than SOC and targeted trials.
Just tell him not to do BAT as it failed and killed a good friend of mine.
PSA rising
Rising PSA after chemo finished.
Rising PSA after 7 Years
Psa rising 
Rising psa
