big jump with PSA: My psa has been... - Advanced Prostate...

Advanced Prostate Cancer

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big jump with PSA

Ian996 profile image
11 Replies

My psa has been steadily increasing for a year now. The doubling time has been consistent at 10 weeks. Until last month.

On July 18 2024 my PSA was up to 56.09 on Aug 9 2024 it jumped up to 179.8

At that time I also contracted a blood infection and a septic kidney stone. I was rushed to the OR on Aug 12 a stint was installed in my right kidney and I have been taking antibiotics ever since. I am scheduled to have the offending kidney stone and stint removed on thursday Aug 29.

So here is the question could the sepsis in my right kidney be the cause of the PSA rise?

BTW I started a clinical trial at BC Cancer for a derivative of Lu177 ( not exactly pluvicto but similar) I have had 2 infusions 8 weeks apart and so far the treatment has not been effective.

A recent Ga68 PSMA PET scan shows new mets on C1 and C3 I have oledr mets on both scapula right collar bone and spots on several ribs

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Ian996 profile image
Ian996
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11 Replies
God_Loves_Me profile image
God_Loves_Me

so many thing going on

- May be dying cells also adding to your PSA number

- other Kidney issues may adding your PSA number

- Clinical trials is not working for sure base on recent Ga68 PSMA PET

I hope you able to find good systemic therapy.

Tall_Allen profile image
Tall_Allen

I hope the new radiopharmaceutical has more effect.

j-o-h-n profile image
j-o-h-n

So here is the question could the sepsis in my right kidney be the cause of the PSA rise?

Ask your M.O. (BTW the word is stent not stint).

Good Luck, Good Health and Good Humor.

j-o-h-n

Lizzo30 profile image
Lizzo30

I would say absolutely yes a kidney infection can cause a high psa especially a septic one I am not a medical person but this is not difficult information to find this is Google AI response

google.com/search?q=can+kid...

I have read many personal stories of men prostate cancer journeys and one man had a concurrent kidney infection problem which raised his psa and his prostate cancer treatment was based on this which resulted in over treatment

Have you looked into estrogen patches for prostate cancer ?

Ian996 profile image
Ian996 in reply toLizzo30

interesting that you mention estrogen patches.

I had a long conversation with Richard W on this very subject on Sunday am

My understanding is that estrogen patches are not standard of Care in BC however I will discuss this with my MO tomorrow

JohnInTheMiddle profile image
JohnInTheMiddle

From what I can see the only drug therapy you received since 2022 when diagnosed with oligometastatic PCa, was ADT?

NecessarilySo profile image
NecessarilySo

I suggest you should read my bio in which I explain how I eliminated my mets using heat and lycopene. You should try it on your spine mets. I also have had a kidney stone removed/disintegrated by laser and since it is done through the penis it could raise PSA if you still have a prostate.

Tinkudi profile image
Tinkudi in reply toNecessarilySo

Where did you read about heat

NecessarilySo profile image
NecessarilySo in reply toTinkudi

Just google heat cancer therapy or similar. When I researched it online years ago, I found that a scientist discovered, in the 1920's, that 106 F will kill all cancer cells.

cancer.gov/about-cancer/tre...

CAMPSOUPS profile image
CAMPSOUPS in reply toNecessarilySo

I recall having lengthy back and forth with you a couple years ago.

I dont mean to pick on you but in the end the mets you say you eliminated were mets you say you "felt". You had no scans that confirmed you had them and then a scan to see they were eliminated. You just felt them. I feel a lot of things with cancer, getting older, and SE's. To assume I can feel a met that hasn't been verified as one is a bridge too far.

On the other hand by now in the journey my scans have shown where the worst of my mets are and were. I can feel those when they act up during progression. Pain.

Like you I have had "knots" , "lumps" in my neck. Those have been muscle related and of course heat and massage relaxes those. They aren't cancer mets that have been resolved by heat.

I just worry that you are misinforming people. I write this to hopefully keep desperate brothers and their caretakers from clinging onto something that wont help.

NecessarilySo profile image
NecessarilySo in reply toCAMPSOUPS

Actually, I did have scans that showed some of them, e.g. the skull mets and neck lymph nodes. The rib met actually was not seen by the radiologist, but I found it on the scan with extreme study. I always eliminated the pains immediately, so during my quarterly oncologist consults, I had no pain to report, and thus, no need to scan. I have no doubt they were metastases...reiterate were. I cannot say my methods would work on anyone else, but I believe they would. Others should judge by themselves. I worry that people are losing their battles because they are misinformed by doctors, who only go down the narrow path of conventional treatments.

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