Perhaps it is related to the night sweats and my body's inability to control it's temperature while I am on these drugs. Between working out more and these hot summer days I find that I sweat FAR more than I used to. I figure it's another drug side effect but wanted to ask if anyone has the same experience or can point me to any studies or writeups on the issue.
TIA!
There seems to be categories of responders, some sweat profusely, some sweat moderately, some sweat a little and some may not sweat at all. .For me, I'm kinda between not sweating and sweating a little...I usually get warm periods for a minute or so. Just sitting under a fan usually does the trick.
I took Lupron for 18 months and decided to to have the boys snipped, for "lifelong ADT". I feel my hot flashes are less since I stopped the Lupron. That's just me though.
Hot flashes are a very common side effect. I had severe hot flashes. I've always worked out. Tried a number of different antidepressants, acupuncture and now Veozah which has finally put a stop to them.
I sweated profusely on warm days when doing any amount physical exertion with Abi pred and Lupron.
Me, too. Middle of the night. Walking for exercise. Heck, sometimes just sitting down to put my shoes on.
(Orgovyx, Abiraterone, and Prednisone)
Yep. On darolutemide and sweat like crazy when I exert the slightest effort.
Sweating more = just another ADT side effect, which I have. I take venlafaxine, use a fan or fans at night, and tell myself "suck it up buttercup." Its better than uncontrolled cancer.
Combo latest injection and extreme heat (96°f) I've been soaking at least 3 shirts per 24 hours. I use 2 fans (eFluky) at night, wouldn't be able to sleep without them.
I was sweating more on average yes.
On the brighter side, zero body odor, although I missed it a little.
It has also never fully returned after stopping, neither did the hair on my calves only.
I'll have to pay attention to the BO thing, haven't noticed any changes there. I noticed the calf hair last week. Not all over, but kind spotty across most of both calves.
I had not thought to relate it to the drugs (Orgovyx and abiraterone), but I am sweating more and smelling less. After a half hour of yard work at 90 degrees, sweat was running into my eyes. Next day, shirt smelled OK so I used it for more sweaty yard work and again no smell. I used to never get sweat in eyes, and clothes would smell.
I have been on all three for 2 1/2 years. Just switched to Orgovyx and the hot sweats are not as bad. I agree though, summers are the worst while on this treatment therapy
I've never been a sweater before Abi-eligard, and Prednisone. But now, the least bit of activity on a warm day, and I'm soaked with sweat. Hot flashes are different than sweating though. Hot flashes are simply the sensation of warmth. With me, hot flashes are preceded by an odd, intense leg pain / numbness lasting several minutes. Then the actual hot flash comes and goes within minutes. When I'm continually active, they are less frequent.
Interesting. Yes, hot flashes and the sweating issue are totally different. Related to the meds for sure, but different experiences. I don't have the leg pain/numbness issue you have. Not heard of that before. Has your doc said anything about that?
Glad to know that I'm not alone. I sweat a lot, especially this summer, and at night too. I also use a fan to sleep. As others noted, I just realized the other day that I don't really smell badly from the sweating. So that's a plus. I'm happy to be living life. Sweat is a small cost. I also have to drink much more water to compensate! Don't forget to do that! Abi has given me strong headaches when I don't stay hydrated!
You might consider low-dose estradiol "add-back". It will eliminate any hot flashes and likely significantly reduce your sweating problem.
Everyone is different. I always have gotten hot at night for long before cancer. After starting Erleada and Lupron it did not get any worse. Best of luck.
I’ve been off abi-pred and orgovix for a little over a year but my testosterone level is still less 100. And I still sweat profusely; a lot more than I used to before adt.
You might consider low-dose estradiol "add-back". It will eliminate any hot flashes and likely significantly reduce your sweating problem. The standard dose is one, large Estradiol (E2) patch per week, strength = 0.1 mg E2/24Hr. Your PCP can prescribe it. You can also use estradiol gel (divigel.com or Estrogel.com), which also require a prescription.
Also, have you considered testosterone replacement therapy (TRT)? If your PSA is stable, then TRT is a safe treatment. Google the 150+ papers by A. Morgentaler about TRT for men with prostate cancer.
I have always been a guy to sweat. Any physical exertion and I sweat. While in the house I’ll have a few episodes where I feel warm for a couple of minutes. I don’t have night sweats. Temp here has been in the 90s regularly and after being outside for a while the sweat is dripping off of my glasses. I look at it as a good way to purge the excess sodium and keep bp in check. God bless.
Bedroom ceiling fan might help a bit.
Yes. Other thqn fatigue, the hot flashes are the worst. I am on ADT after radiation. I wake up several times a night with tons of sweat on my upper lip and forehead, dripping for some time. Depending on how severe, I use ice packs an ice vest, and fans. I am taking some naturopathic stuff that helps reduce frequency and severity, but always there every day.
You might consider low-dose estradiol "add-back". It will eliminate any hot flashes and likely significantly reduce your sweating problem. The standard dose is one, large Estradiol (E2) patch per week, strength = 0.1 mg E2/24Hr. Your PCP can prescribe it. You can also use estradiol gel (divigel.com or Estrogel.com), which also require a prescription.
Thanks! I've been able to sleep some nights without interruption using herbs to manage the hot flashes. I'll keep your advice in my back pocket for my next MO appointment!
When I hear the words "I do" I tremble uncontrollably and sweat profusely.....
Good Luck, Good Health and Good Humor.
j-o-h-n
PARP inhibitor Olaparib, phase 3 study findings (PROpel)
MRI prior to HDR Brachy and HDR intensity.
PSA holding low!!
