If immediately stopping after two ye... - Advanced Prostate...

Advanced Prostate Cancer

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If immediately stopping after two years taking Orgovyx how long before testosterone begins to rise?

SViking profile image
14 Replies

I’ve heard that testosterone returns quicker if using Orgovyx compared to Lupron. But I also heard that the longer on any ADT the longer the recovery. Or maybe testosterone never recovers? What do you guys think question

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SViking profile image
SViking
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14 Replies
GP24 profile image
GP24

There is data for about one year: 90 days for testosterone recovery.

orgovyxhcp.com/efficacy/

I personally would continue with Bicalutamide which will increase the testosterone level.

SViking profile image
SViking in reply to GP24

thanks. Does bicalutamide also cause men boobs?

GP24 profile image
GP24 in reply to SViking

Yes, it does. But it also works against prostate cancer while just stopping with Orgovyx will leave you without therapy. You can take Tamoxifen against boobs.

Seasid profile image
Seasid in reply to GP24

Whats about radiation to the boobs? Would it help?

GP24 profile image
GP24 in reply to Seasid

Yes, it will help, but Tamoxifen is more effective I think.

Justfor_ profile image
Justfor_ in reply to SViking

The weakest point of Bicalutamide is its low price. One month's supply of the original Casodex costs here 44 Euros, while the generic "Bicalut" almost half of that.

Seasid profile image
Seasid in reply to Justfor_

I don't understand why is low price a weak point?

Justfor_ profile image
Justfor_ in reply to Seasid

Because there are non-existing margins for promotional campaigns. As a result Bicalutamide is bad mouthed as a thing of the past, not-potent enough, etc, with the industry's effort being to shift patients towards the second generation lutamides which, being under pattern, cost 20-50 times more, facilitating promotional campaigns. In my case Bicalutamide is pure "dynamite". I purposely keep my PSA at the lower limits of lab detection with only one 50mg pill every 8 days!

Seasid profile image
Seasid in reply to Justfor_

Thanks for explaining me. What is the biological half life of the drug if you can take it only once in 8 days and it is effective? Or is it so because of some other reason?

Seasid profile image
Seasid in reply to Justfor_

Are you taking something else or just bicalutamide?

Justfor_ profile image
Justfor_ in reply to Seasid

1) Short answer re half life 5-7 days. I split a 50mg Bicalutamide tablet into 2 and take half every 4 days. Long (to very long) answer here:

healthunlocked.com/prostate...

2) I take Avodart daily and 10 mg Tamoxifen (to counteract Gynaecomastia) 3 days out of four starting with the day of half tablet.

Seasid profile image
Seasid in reply to Justfor_

Thanks

Murph256 profile image
Murph256

After one year on Orgovyx, my testosterone recovered in about 6 weeks after I stopped. This is much faster than Lupron. My T did not recover until 8 months after my second “3 month” Lupron shot.

SViking profile image
SViking

How to wean off of Zytiga? I've been on one capsule (250mg) every other day with 5mg Prednisone everyday. How to wean off these drugs together?

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