Veterans Administration , SOC

[reconjj]

Hello Ladies and Gents , I go to Hines V.A here in Illinois . My MO there is a Loyola MO. Im currently in my 14th month of Eligard , Zytiga , prednisone . They are on the 2 yr plan of stopping treatment and see what happens . Is V.A stuck on that SOC ? Im undetectable right now but have 10 months to go for that 2 yr plan . My question is which Im going to ask her next week is , if I choose , can I continue with these drugs into the future until they fail rather than let the monster loose . I had 1 tumor in a lymph node radiated , SUVmax24 , then 25 radiations to my pelvic area . Tall Allen put out a link in the past of possible cure with the treatment I had . Any thoughts are appreciated .

[Derf4223]

ADT+Abi are given to patients in MCRPC status plus other drugs. The other drugs rely on ADT+Abi. SoC is the foundation other treatments are built on. Some of those drugs are being approved for earlier pre-CR albeit narrowly defined patients. Also one may explore getting into a trial, but they have their own narrow criteria and goals.

One of the biggest things one can do in order to reduce odds of PCa mortality is lots of exercise. Search that here.

Also, it is easy to overlook the other monster in the PCa closet: accelerated bone loss. I personally take 2x600 mg Calcium plus 2x2000 IU D3 at bedtime and wee-wee time #1, along with Magnesium at bedtime. I also take K2 Mk 7 100 mcg and K2 Mk 4 45000 mcg with dinner. All of this along with Prolia.

Have you had a DXA scan?

A lot of my supplements and vitamins offset deficiencies arising from eating a meat/dairy/egg-less diet big on vegetables and fruits. Meat/dairy/egg are all said to be bad for PCa.

[Tall_Allen]

The latest data is for 2 years of Zytiga and 3 years of ADT. Then stop. Hopefully, you will be cured. Email this to your oncologist:

ncbi.nlm.nih.gov/pmc/articl...

[reconjj in reply to Tall_Allen]

Thanks Tall one , but this applies to non-metatastic men . I had the 1 tumor in my lymph node so I would be metatastic , correct . Maybe Im reading that wrong ?

[Tall_Allen in reply to reconjj]

No, it applies to patients just like you who have cancer only in pelvic lymph nodes and not at distant sites. You are stage N1. I know the language is confusing, but when they say "non-metastatic," they mean non-metastatic in distant sites, which would be stage M0. You would not be called "metastatic" by their nomenclature. To avoid confusion, it is better to think of your situation as N1 M0, which may be curable.

[tango65]

TA is correct. The information you provided shows the cancer is N1M0 (no metastatic). Two years of ADT and abiraterone plus 1 extra year of ADT is the best option at this time. Then stop and hope for the best.

[reconjj in reply to tango65]

I will take this to the bank for now . I hope my V.A. MO agrees with this study. If V.A. MO says no to this study I get no drugs . So we will see .

[tango65 in reply to reconjj]

This is the link to the Stampede trial which includes N1M0 patients (nodal relapse, no distant mets).

ncbi.nlm.nih.gov/pmc/articl...

[Bronzee]

i have been on Abirateron1000 mg and prednisone 5 mg. for 5 years. I also have injections every 6 months. My onco uro believes it is working to my advantage as mets to iliac and 1 lymph node have been arrested If it aint broke, why stop? My PSA is 0.01