Hot flashes and mood swings

[Knittingque]

Taking Zoladex again for recurrance of prostate cancer, hot flashes and mood swings are really bad this time around. l have been given a script for Cyproterone 50mg to ease symptons. Anyone using or have used this for the same reasons. Comments would help.

[Derf4223]

On Lupron+Abi, I manage hot flashes with MO-prescribed Venlafaxin (37.5 mg works for me, can go up to 75 mg/day.) HF's are not eliminated but rather smoothed out in lower intensity and no sweating.

[Knittingque in reply to Derf4223]

Thanks for sharing

[Wassersug]

Sorry to heard what you are going through with ADT and hot flashes. You have many options and should not have to endure severe hot flashes.

The third edition of our book "Androgen Deprivation Therapy: An Essential Guide for Prostate Cancer Patients and their Loved Ones" has just been published. Compared to the 2nd edition, it is greatly updated and substantially expanded. In particular, there are several pages there on alternative ways to reduce hot flash incidence and bother.

The advice in the book about managing ADT side effects, including hot flashes, is evidence-based which accounts for the book getting formal endorsements from both the Canadian Urological Association and The European Association of Urology.

I hope that is helpful.

Richard Wassersug

North Vancouver, British Columbia, CANADA

[Knittingque in reply to Wassersug]

Thanks so much

[treedown in reply to Wassersug]

Thats a bummer I bought the book a couple months ago. Hopefully there's not too much new info. I am getting your blog posts which I am finding informative so thank you.

[EdBar]

I manage hot flashes with estradiol patches originally prescribed by Snuffy Myers, been using them for years. They work like a charm and are good for bone health as well.

Ed

[Appraiser in reply to EdBar]

hey Ed……could you tell us what the dosage is

Thanks

Joe D

[EdBar in reply to Appraiser]

0.1 mg, I use 2 patches per week, so in other words I remove one patch after 3-4 days and stick a new one on every week. Works great, I used to get severe hot flashes about every hour, now I rarely if ever get them.

Ed

[Appraiser in reply to EdBar]

thanks Ed…….are they expensive?

[EdBar in reply to Appraiser]

No, they are covered under my Medicare Drug plan.

[Appraiser in reply to EdBar]

awesome……..thanks again Ed

[ARIES29 in reply to EdBar]

Not here in OZ ed, the medics have their heads still stuck in the sand here.

[Knittingque in reply to EdBar]

Thanks for sharing appreciated

[Jack54 in reply to EdBar]

I agree 100% with Ed. Worked great for me.

[j-o-h-n]

Cyproterone (from Wikipeedonme)

Males

CPA has been found to be effective in the treatment of acne in males, with marked improvement in symptoms observed at dosages of 25, 50, and 100 mg/day in different studies.[53][54][55][56] It can also halt further progression of scalp hair loss in men.[57][58][59] Increased head hair and decreased body hair has been observed with CPA in men with scalp hair loss.[60][13] However, its side effects in men, such as demasculinization, gynecomastia, sexual dysfunction, bone density loss, and reversible infertility, make the use of CPA in males impractical in most cases.[57][58][54][55][61][62][63] In addition, lower dosages of CPA, such as 25 mg/day, have been found to be better-tolerated in men.[55] But such doses also show lower effectiveness in the treatment of acne in men.[53]

j-o-h-n <===<<< Senior management is about to spike my spikes....

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 04/14/2023 7:13 PM DST

[Knittingque in reply to j-o-h-n]

Thanks so much

[inthefight]

Venlafaxin 37.5 mg has helped my hubby with his hot flashes to a certain degree.

[Knittingque in reply to inthefight]

Thank you

[Ian99]

Hi. I’ve been on Zoladex for 20 months. Also Zytiga + Prednisolone. I get 1-2 hot flashes every day on average. I just go outside to cool down. Trying to avoid additional medication. Overall I find it tolerable. Good luck.