Anyone with experience of FWGE? TNVAN... - Advanced Prostate...

Advanced Prostate Cancer

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Anyone with experience of FWGE? TNVANS asked the same question 3 years ago, but now there is this paper on a pilot clinical trial.

Graham49 profile image
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Fermented Wheat Germ Extract (FWGE) as a Treatment Additive for Castration-Resistant Prostate Cancer: A Pilot Clinical TrialRony Weitzen, Nava Epstein, Bernice Oberman, Rebecca Shevetz, Mate Hidvegi, Raanan Berger

Nutrition and Cancer 74 (4), 1338-1346, 2022

Castration-resistant prostate cancer (CRPC) is a devastating and incurable disease. Combined therapy using conventional anticancer drugs and a proprietary medical nutriment, fermented wheat germ extract (FWGE), also known as Avemar, has been suggested as a treatment for progressing prostate cancer (PCa) patients, who have become resistant to first line hormonal therapy (gonadotropin releasing hormone, GnRH). The primary aim of this study was to test if this combined therapy would slow down disease progression in CRPC patients. We tested the nontoxic, readily available, inexpensive FWGE, together with the conventional treatment, GnRH analogue, in 36 CRPC patients. Although this is a pilot study, with the drawback of a statistically small sample size, some anticancer clinical activity of FWGE could be seen in the CRPC patients, as measured by prostate specific antigen doubling time (PSADT). We found that the intake of GnRH with FWGE for at least 4 months, improved the overall health as well as the quality of life (QOL) in 4 patients (11%) and was instrumental in extending the PSADT in about 17 (out of 26) patients (65.4%), six of whom were significant. Since no mentionable adverse events were noticed, this treatment may permit the postponement of chemotherapy for these patients.

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Graham49
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Okay4now profile image
Okay4now

My one experience with chemotherapy was in 2001. I took part in a clinical trial involving estramustine, taxotere (docetaxel) and lupron. I lost all my hair, all my nails, and my eyebrows took 4-5 years to reappear. The psa dropped during the trial, then went back up. I wouldn't wish that crap on anybody.

Graham49 profile image
Graham49 in reply to Okay4now

FWGE is nothing like estramustine and taxotere. Its a supplement you can get online.

Okay4now profile image
Okay4now in reply to Graham49

I understand; I was only responding to the mention of chemotherapy in your last sentence.

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