Follow up with VA Testosterone Trial - Advanced Prostate...

Advanced Prostate Cancer

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Follow up with VA Testosterone Trial

michaelcc profile image
8 Replies

July 21st I completed my blood work and received my next testosterone shot. My ALP was 63 but my PSA numbers are climbing with a 14.4 result.

I left out of my last post that I have three cancer areas on my spine where the neck area is the worst. I've had radiation on my neck twice at the end of 2019 and likewise the end of 2021. They are hopeful that the radiation destroyed 70-80% of the cancer yet that result is still disconcerting. I can't radiate that area any more.

So, your results from the testosterone may be more optimistic. I have to rely on the scans more than just PSA numbers but it appears that my trial may be winding down. As said earlier at least I've had a break from the other protocols and have enjoyed the feelings of normalcy.

Michael

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michaelcc
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8 Replies
Shooter1 profile image
Shooter1

Darn, I wanted glowing results as I am starting T treatments in Aug.... My MO has nothing else in his bag of tricks.

CAMPSOUPS profile image
CAMPSOUPS in reply to Shooter1

Im glad August is around the corner. I am glad you can get into a trial. I have optimism. I think even after this trial you have other trial options (CAR-T) etc.

In the meantime you hang in there brother!

Ramp7 profile image
Ramp7

Last week I received my 3 month Lupron shot. The MO mentioned one of his patients is on a BAT trial and responding well.

beckymb3 profile image
beckymb3

Something important to keep in mind is that in the Denmeade JH trials one of the significant outcomes of the BAT / testosterone cycling is that BAT would resensitize the patients to the effects of enzalutamide (Xtandi). Some theorize that patients could alternate between BAT and enza treatment for an extended period of time. This may be an option, rather than moving on to other treatments, at least for a while. This trial showed enza had better rechallenge results than abi. pubmed.ncbi.nlm.nih.gov/326...

MateoBeach profile image
MateoBeach in reply to beckymb3

Excellent and important point!

MateoBeach profile image
MateoBeach

What is the treatment protocol on the trial, Michael? Is it the standard BAT or something modified? Paul

nuc1111 profile image
nuc1111

Could you elaborate what testosterone study your on? thanks. Ed

michaelcc profile image
michaelcc

Testosterone shots only, but I'm going to talk to my medical oncologist about mixing up the protocols as the trial comes to a close.

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