Recent Auxmin and PSMA scans show that my husband has BCR oligometastesis (MRI shows nothing). It seems there are two different treatment options/opinions:
1. Lupron OR Eligard OR Firmagon OR Orgovyx for a few months and then radiation, then continue hormone therapy for 1-1.5 years
2. Lupron OR Eligard + Zytiga for a few months and then radiation, then continue hormone therapy
There seems to be indication that Zytiga causes early hormone resistance. We are a bit concerned.
What's your experience/thoughts on what hormone therapy to take? If it's a combination of Lupron + Zytiga, do you take them simultaneously or do you take Lupron for 1 or 2 months or 3 months and then add Zytiga? What dosage each?
My husband's medical background:
Diagnosed in Dec 2019, Gleason 7 (3+4), PSA 4.5, CT scan: Clear, Bone scan: Clear. 3T MRI showed ECE. Had 6-week proton therapy in June/July 2020. No hormone therapy. PSA went up in March 2022 and did Auxmin and PSMA scans. He has a stent in his heart.
Thanks very much.