Zytiga progress update

[Rogersw]

Hi following on from my earlier post I’m approaching the end of my forth week and I would say it is not that much different to Lupron except I find the fatigue and minor ache are more intense (both seem to come and go). My hip pain does seemed to have eased. I was give a full blood test at three weeks and all result were normal except my psa which has gone up so I’ve started getting concerned that Zytiga might not be for me. Time will tell I guess.

[tango65]

May be the PSA is going up because the cancer cells dying with the treatment. I would wait to see if there is a persistent increase in the PSA before starting to really worry about the efficacy of the treatment.

[Dastardly]

I've just finished my first month on Zytiga/Prednisolone. I feel noticeably more tired and my blood pressure is starting to rise. My PSA has dropped from 0.52 to 0.24. I also seem to be getting more lower back pain as well, although that could be anything.

[Jost-58 in reply to Dastardly]

Exactly as my PSA

[Chrisbaird]

Rogersw. Zytiga has worked well for me for 16months PSA remained low @ 500gm daily with prednisone 5gm and three monthly HT jags only symptoms fatigue/energy levels hope your PSA levels are lowers rate after a period 👍🏻

[leo2634]

Give Zytiga a chance. I have been on it plus Eligard for over four years now and PSA has been 0.1 since the start of treatment. I've also had Provenge infusions during my first year diagnosis. Never give up Never surrender. Leo

[MrDon2 in reply to leo2634]

Have you ever taken a "vacation" from Eligard in your four years? I been on this combo for two years and my uro doc mentioned if I wanted to take a break from the Eligard I could.

[leo2634 in reply to MrDon2]

No I've been on this treatment since day one of diagnosis. I'm not really entertaining the thought of vacation and neither is my Doctor. I'm a firm believer in if it ain't broke don't fix it. I've gotten used to the ups and downs of ADT and all in all its keeping me alive. I'm sure people will debate the vacation thing but I have complete confidence I'm my Doctor and his team. If down the road he suggests it then so be it. I just had my visit with him on Wednesday and got my six month Eligard injection. My doctor says he couldn't be happier for me and my results. Leo

[MrDon2 in reply to leo2634]

I am trending to continue all of my meds, just as you have. As you mention, if it is working don't change it. Wish you the best of luck.

[leo2634 in reply to MrDon2]

Don't go be me be your own advocate. I'm just one of many. I trust my Medical team literally with my life. I don't do anything he says not to. He promised me to keep me alive to watch my Grandkids grow up so far so good. Leo

[Bunkerboy]

I’ve been on Zytiga since Jan 2015. Side effects not good especially being tired all the time and sweats. Push myself to get moving and find as long as I’m up and about not too bad. Weight and fat belly annoying but manageable. My docs are happy as my PSA is at 0.008and Tes at 0.4. Been that way for years. But understand definitely not the same for everyone.

[Hidden]

Unfortunately Zytiga was not helpful to me. I then went in Xtandi and had better results for awhile. Good luck!