Generic Zytiga vs. Zytiga

[leo2634]

Good morning to all of you my Brothers.

I've recently been put on generic Zytiga only into it a few weeks but I've noticed since the switch it seems to be doing a job on my stomach which the real Zytiga never did. I don't know if it is in my head or not but definitely in my stomach. By the way neither the real Zytiga or the generic are film coated so that's not an option for making my case. I also don't see the big hype on generic verses the real Zytiga it isn't much more cost wise at least not with my insurance and supplement plan. Any thoughts? I'm going to see my Doctor on May 1st and present this to him. Never give up never surrender. Leo

[FCoffey]

The generic versions have the exact same molecule, and if the tablet composition is the same, it's hard to see how it could be the generic's fault.

Perhaps other factors have made your gut more sensitive. Diet, stress, interactions with other drugs, the list of things that upset the gut is long. It might even be that your gut was objecting to Zytiga all along, and now that treatment has resumed your gut is already sensitized.

Eliminating things from the diet can often help, but it takes time and can be frustrating.

I hope you can find relief. Good luck!

[leo2634 in reply to FCoffey]

Already started that . I've never had a break from Zytiga just went right to the game when the last of the Zytiga was taken after about the fourth day on the generic stomach problems started.

[FCoffey in reply to leo2634]

Diarrhea and Dyspepsia are relatively common side effect, 18% and 6% of patients, respectively, report them. The prescribing info and marketing materials for Zytiga don't seem to mention anything done to change that.

[CantChoose in reply to FCoffey]

The fillers are often not the same. Inactive ingredients can make a surprisingly large difference.

[Gearhead]

Been on Janssen (non-generic, I think) Zytiga for about 3 months. No upset stomach problems. Have always had moderate constipation , which seems to have gotten a bit worse since starting all my ADT + bone drugs, so can't really blame that on Zytiga alone. Zytiga costs me about $2,500 first month and now about $520/month (Medicare Part D...went through "doughnut hole" fast). That upset me in general but didn't focus on my stomach. Good luck and I hope your stomach issues subside.

[leo2634 in reply to Gearhead]

Thanks I'm thinking or rather hoping it's just a stomach bug. Who knew I'd be wishing for a bug huh ...

[MMMayhem]

I realize this may not help, but I was on ADT for 9 months and switched twice without any stomach issue. I was on Zytiga from last July through the beginning of this month. Last fall they switched me to the generic and I didn't even notice (my wife will testify I'm not the most observant man on the planet). I was on CarePath through Janssen so I discovered it in January when my copay was thousands of dollars because Janssen only covers their product. So for Jan I went back to name brand. Then in Feb after they got me on copay assistance for the generic I went back to that.

Never had issues so I'm inclined to agree the cause is something else and the timing is coincidence. Though I haven't checked to see if there are fillers and a difference in them might be what you're sensitive to. Anyway, good luck.

Mark

[michael00]

Im about to be switched to generic by my insurance company. I'm hoping for no difference because zytiga never bothered my stomach but MO prescribed prilosec with it and i wonder if that has helped

[Hidden in reply to michael00]

I switched two months ago. Not noticing any difference yet. It is a couple hundred a month cheaper.

[michael00 in reply to Hidden]

My insurance company gets a lower cost but my cost will actually go up due to losing the janssen copay assistance

[Hidden in reply to michael00]

I wanted to stay with the Zytiga just because things were working. So I assume you are staying with Zytiga?

[michael00 in reply to Hidden]

I want to stay with zytiga because it works but insurance company moved it to nonformulary list. When i pointed out i had nonformulary coverage they moved it to uncovered/excluded drugs list. The only way to get partial coverage is get my MO to put in writing medical reasons not to switch

[Hidden in reply to michael00]

You won’t get that one. I called Jansen to see if they would help me but if you are on Medicare you are out. Otherwise they would sign me up if I could qualify.

[leo2634 in reply to Hidden]

I'll know tomorrow when I see my Doctor.

[Jimdoud1]

I haven’t noticed any difference.

[Joes-dad]

This won't exactly help but I was taking two 500mg coated Zytiga a day for about my 1st year. In January my insurance switched me to the uncoated 250mg generic Zytiga. I had heartburn every morning after taking the generics which never happened with the 500's. The heartburn stopped after a couple of months though. A small price to pay. Psychologically I'd rather be taking the original Zytiga vs a generic...

[leo2634 in reply to Joes-dad]

I agree but insurance thinks different. I guess it's not thier gut hurting.

[j-o-h-n]

Are you taking the Zytiga with water vs generic water?

Good Luck, Good Health and Good Humor.

j-o-h-n Tuesday 04/30/2019 7:51 PM DST