iADT if BCR post surgery / radiation / chemo -- then nothing but Avadart, Curcumin, Resveratrol, Mediterranean diet and daily exercise, in some cases T replacement with active residual cancer. He is 20 + years since diagnosis metastatic PCa.
askdrmyers.wordpress.com/20...
askdrmyers.wordpress.com/20...
He talks about taking Leukine ?? as part of his initial treatment
Too bad he is being held to things he posted a decade ago. When I get time, it reminds me that I should remove my articles that are either no longer relevant or where higher levels of evidence have proven lower-level evidence wrong. I try to update some, but there are several hundred.
They are still doing it -- 2016 till he retired
There are 62 studies on clinicaltrials.gov for leukine for PCa. Only 2 of them are recruiting. 27 have results. The ones that I looked at showed some efficacy, but it requires a multiple-hour IV drip 3x a week and use might be applicable to chemo for white blood cell regrowth. If someone is interested, I can put this on my list of questions for my MO.
malecare.org/leukine-a-seco...
clinicaltrials.gov/ct2/resu...
I haven't watched the second video.
What is the role of Avodart, mechanics wise, in his preventative protocol? Tried google but was not helpful.
you should read the article and discussion about finasteride and Avadart here:
Avadart blocks the ability to convert Testosterone to DHT --which DHT is the driver of prostate cancer progression ....
the New England Journal of Medicine:
"Men deficient in an enzyme called 5-alpha-reductase type 2 DONOT develop an enlarged prostate (also called benign prostatic hyperplasia, or BPH) OR PROSTATE CANCER. Without 5-alpha-reductase type 2, testosterone can’t be converted into DHT, which promotes prostate growth. (See “Two enzyme types,” below.) "
Celebrex (celecoxib): ncbi.nlm.nih.gov/pmc/articl...
From what I've gathered, Snuffy was very experienced treating PCa patients but some of his protocol(s) didn't have much high-level evidence, other than anecdotal evidence from his own clinic and with patients taking multiple things at once it makes it impossible to determine what really makes a difference and what doesn't.
But the statement...
"then nothing but Avadart, Curcumin, Resveratrol, Mediterranean diet and daily exercise"
reinforces the direction with my own research journey. I am personally convinced that Advodart is an important tool at the right time in the PCa journey, and diet and exercise are no brainers. So it is insightful. out of the dozens of other things you can take/do, Reservatrol and Curcumin are all that survivors?
My guess is he considered Curcumin to be superior to Baby Aspirin (that they were in the least, duplicative in the Thromboxane (TXA2) suppression aspect. But the dosage regimen for Aspirin is well researched where Curcumin is a complete guess comparatively, both on type and amount)
New Study pinpoints LSD1 inhibition as potent disrupter of androgen binding and transcription, dramatically slowing prostate cancer growth
Next steps after Prostatectomy?
PSA increase with anxiety
