About a week ago there was a zoom meeting sponsored by the prostate cancer foundation. there were special sessions the second hour. i joined the one on advanced prostate cancer there were all sorts of technical issues and i did not have the ability to ask questions. i believe the first hour (1/4 of which was wasted with technical problems) was recorded but i don't think the special sessions were.
there were two brilliant women doctors one of whom talked about targeted radiation using Liu 177 or whatever it is, for advanced but castrate sensitive PC. this issue has been avoided and there are essentially no trials, the idea is to wait until you have suffered the effects of ADT for years and you are close to death. this doctor suggested that it might make sense to start earlier. she might have even mentioned a trial or the hopes of one. Does anyone know who this doctor is and maybe how to contact her?
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spencoid2
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I understand that they want to die but wouldn't it be cheaper to cure you instead of paying for a bunch of other treatments and then eventually the same drug when it won't work. I don't understand big business but I am sure they have it all figured out. Do you think they are selling a lot of it off label at absurd prices the insurance companies would never pay.
On another rip off topic. Aberaterone varies in price and in the US we pay the highest possible anywhere. I looked up the process for making it thinking it might be some really exotic method and expensive to make. It is not the recipe was for 55 gallons and it used common chemicals and processes, nothing special at all and they make billions on 55 gallons and then tell us we need to take 4 because even though one will do with a fixed calorie low fat (i think)meal they will not run trials on it because it will cut into their profits. They do exactly this in places like India where they won't tolerate bullshit as much as we have been trained to.
Himisha Beltran of Dana-Farber was one of the main speakers. Go to their web site and insert prostate cancer and she pops up #1. Great overall presentation...
i will, how did you find her address, i did a fair amount of looking and found a lot about her repeated on many sites but was never able to find her email address. thanks a lot.
Thank you for this. UK here but good to see this as a trial. Following on from Nalakrats, I wonder why it is limited to Oligo only and not all Hormone Sensitive with Mets. I wish that pharma would look at all of us
I believe they want to compare if it is the same or different to treat oligo with direct treatment (local treatments) or with Lu 177 PSMA (systemic treatment). Perhaps they are trying to show that a systemic treatment is better .
Remember they not treat with Lu 177 PSMA unless they see the metastases (4 mm or more) but Lu 177 PSMA may treat mets that are not seen with the current machines resulting in a more comprehensive treatment. Nobody knows yet.
this is the summary which i believe says they are using both not comparing them
Brief Summary:
The researchers are doing this study to find out whether combining 177Lu-PSMA-617 with SBRT is a safe and effective treatment in people who have hormone-sensitive oligometastatic prostate cancer. The researchers also want to learn more about how the study treatment affects daily life and the symptoms of cancer. This study is the first to test the combination of 177Lu-PSMA-617 and SBRT in people.
Interestingly the same can be said for Provenge. Their trial when looked at by tiers of different PSA levels showed better snd better results the lower the starting PSA. Yet no trials for hormone sensitive. That’s why I paid out of pocket to do it now, while still hormone sensitive.
I’m not sure however, that I follow your hypothesis as to why this happens. It seems like if they proved a drug worked at hormone sensitive stages, they would open up thousands of new patients who would use their drugs for much longer time periods leading to higher profits. Once we die, we can not be profitable. Seems like something else is at play.
i understand a lot of what you are saying and agree, it is all about money not keeping people alive and not miserable. there are other drugs that have been around forever and what they did was jack the price up ten fold or more. and we in the US pay for a major part of the development of new drugs at universities and do not benefit from it. "they" are now saying that the problem with our economy is that we are not subsidizing big oil enough, the most profitable industry on the planet and we have to subsidize them. what about subsidizing the small businesses from which many new and useful discoveries are made?
about ivermectin, do you think it is too risky to take animal products? the Tractor Supply still had one vial of injectable left but maybe that is no longer available. i thought the injectable made the most sense because you are sure it would be homogenized. i was going to buy it by my husband said he would never take animal drugs. i would think that the animal drugs are made to the same standard as those for humans. funny but most of the paste stuff flavored to the likes of a horse were sold out but people were afraid of the injectable thinking they needed to inject it?
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