Docetaxel

[Fight11]

My husband has been on Zytiga, Lynparza as well as Keytruda all which have failed. He is now on Docetaxel he had his fourth round today. Psa does not seem to be responding. He will have bone scans and ct scan.Is there something he can take in conjunction with the chemo? If this treatment fails I don’t know where to go from here. Could any of you maybe share a similar story and what would be next as a possible treatment. Feel so defeated and petrified. Thank you so much

[Hidden]

If Docetaxel is ineffective, he can switch to Cabazitaxel (Jevtana). That can work in cases where Docetaxel is ineffective and generally has less side effects for most patients.

LU-177 may also be an option if you can travel and have the funds. For that, it needs to be determined if the patient is PSMA avid. That's done through a PSMA PET scan.

It should be FDA approved soon in the US.

[NotAlwaysSunshine]

Hang in there!! What gregg57b said.. Jevtanna ! Do you have a date for scans?

[Fight11 in reply to NotAlwaysSunshine]

No they will be calling with the dates. Something has to work

[Yadifan]

I'm so sorry Fight11. I wish there was a "don't like" button I could push for this post. It does sound like there are other options. I know that Jevtana is on deck for us. Hoping for a successful next step for you. Hang in there.

[Shooter1]

With chemo for me PSA was climbing after number four so we added xtandi after # 5 and it came down again... Best of luck to you.

[Fight11 in reply to Shooter1]

How many rounds of chemo did you have? Did you stay on the Xtandi after chemo?

[Shooter1 in reply to Fight11]

Total of 9 cycles and still on Xtandi, but only half dose. Full dose made me an invalid...

[Nous]

hi Fight11 ,,, sorry to hear about the challenge you are trying to overcome ... perhaps take a look-at these websites ... envita.com ... drgeo.com ... best wishes ... Nous

[NWLiving]

Bill had Xtandi combined with the dosetaxel too. It kept the beast at bay for over 3 years with pretty minimal side effects.