ADT Vacation - first month being off ... - Advanced Prostate...

Advanced Prostate Cancer

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ADT Vacation - first month being off Firmagon. PSA was .014 & Testos. 3 - After a month vacation - PSA .08 & T159 - any thoughts?

Longterm101 profile image
12 Replies

I was a gleason 9 with lymph node involvement. No distant mets. Did HDBrachy with 25 sessions of IMRT.

I was DX 2 1/2 years ago. This is my first vacation . I'm off all drugs.

I've been on Firmagon for 2 1/2 years.

Stopped 35 days ago.

Small PSA rise and T went up considerably.

I still have my prostate.

Thoughts welcome

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Longterm101
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12 Replies
pjoshea13 profile image
pjoshea13

PSA will tend to rise as T increases through the hypogonadal range. Morgantaler's androgen receptor saturation point is around 250 ng/dL. You have to get above that to see what the PSA trend is. Don't read too much into early numbers.

Best, -Patrick

kainasar profile image
kainasar in reply topjoshea13

So it could be a number of months before PSA rates are meaningful, no? At what PSA level should one get back on ADT?

pjoshea13 profile image
pjoshea13 in reply tokainasar

See: pubmed.ncbi.nlm.nih.gov/315...

Tall_Allen profile image
Tall_Allen

Why do you call it a "vacation"? Isn't adjuvant ADT over, hopefully?

Longterm101 profile image
Longterm101 in reply toTall_Allen

TA I’d love that to be the case !!

Unfortunately I understand the real situation I’m in!!!

Im praying for a miracle

Pretty quick Testosterone recovery. Bet it feels good. Seems like with just radiation you should be happy with anything that low even if it appears like a modest increase

Longterm101 profile image
Longterm101 in reply to

Good question ….

My plan was to keep measuring the PSA and T levels every 30 days

Once my PSA got above 1.5 - 2 get a PSMA scan to get better insight

Any thoughts

in reply toLongterm101

I think that's right and enjoy life now. What will be will be but you feel good now and it may last for many years.

Longterm101 profile image
Longterm101 in reply to

thx .... god willing!!!

Boywonder56 profile image
Boywonder56

Get back on the adt pony

timotur profile image
timotur

Keep tracking T and PSA and see how things look when your T reaches the normal range. If PSA rises above 0.5-0.7, investigate a PSMA scan. Best wishes.

Mascouche profile image
Mascouche

The end of my adt treatment is still 18 months away but when I asked my RO about psa rising once adt is over, he said that there is no follow up treatment required until the psa reaches at least 2.

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