Lupron + Casodex treatment for my lymph node metastases (multiple pelvic and abdomen nodes) was started in November 2018 with a PSA of 4.48. By November, 2019 the PSA dropped to 0.06, when on doctor's advice I started a vacation from ADT. Three months later my PSA is 0.07. My last 3-month Lupron was in September, 2019. I am still waiting for my Testosterone result. I suspect it is still in the castrate level. Previously, when I was on Lupron for six months, it took about six months for Testosterone to come above castration level.
Making allowance for statistical fluctuation, my PSA stayed at the lowest level over the last six months. It appears that my metastasis is still hormone sensitive. I expect my PSA to start rising over the next six months. I don't expect my quality of life improve significantly during ADT vacation. How much should I let PSA rise before starting ADT again?
PSA History: Nov 18: 4.48 (start of ADT + Casodex), Feb 19: 0.17, May 19: 0.10, Sept 19: 0.07, Nov 19: 0.06 (start of ADT vacation), Feb 20: 0.07