Lymph’s nodes relapse

[Johnko]

Good morning

I am writing on behalf of a friend who doesn’t speak English to get some advice.

My friend has been diagnosed 4 years ago with agressive localisée prostate cancer .

He first went through radical prostatectomy and since his nadir psa was 0,23 and pathological report was not good he got adjuvant radiotherapy plus one year of lupron. His psa became undetectable but then started to rise again last year from 0,1 to 0,63. He did a PSMA scan in February showing 2 positive lymph nodes in the L2,L4 region. First of all I don’t understand why his doctors waited so long to treat him. They are now offering him 25 sessions of radiotherapy and 1 year of lupron.

I have been doing a lot of research and according a video posted by Dr Scholtz from PCRI, my friend would be in the high indigo stage and then would required to be treated with radiotherapy plus lupron plus second generation hormone therapy and a set of 6 sessions of Taxotere to still give him a chance to get cured.

My friend just got his first lupron injection and is in the middle of his 25 cycles of radiotherapy.

Thanks for your advices.

[Johnko]

Any advice?

[wolf2gang120 in reply to Johnko]

I did 38 radiation treatments and 3.5 years of Lupron shots, plus casodex .I'm still alive 10 years later with a psa of .03 since. Its his decision and his families, but it gave me hope. My psa started out at 102.....good luck

[Tall_Allen]

I have no idea what indigo means, but his situation is recurrent, metastatic (stage M1a) and hormone-sensitive. Because he is only metastatic on a PSMA PET and not on a bone scan, there are only a few small studies that suggest that early treatment with 2nd line hormonals may be beneficial. There is nothing to suggest that such treatment can be curative.

Docetaxel is beneficial when one is newly diagnosed as stage M1a on a bone scan. But is it still beneficial when a man is recurrent and the only metastases are detected with a PSMA PET scan? My guess is yes, but I am just guessing.