Now discovered prostate cancer on 3/2017, removed on 6/17. Psa going up on 8/17, and radiation on 11&12/2017. Good for 2 years, but now at .4 and taking Lupron (just Started). Wondering what people think of castration vs chemical castration. Pet scan shows spot on one lymph node and where urethra attached to bladder. Polaris was 5. Thanks
Psa rising and on Lupron. Thinking a... - Advanced Prostate...
Advanced Prostate Cancer
Psa rising and on Lupron. Thinking about castration and looking for advice.

If the spot was on a pelvic LN, you can try getting all your pelvic LNs irradiated, in addition to the SBRT to the single site on your bladder neck.
The only reason to not have an orchiectomy is if you foresee ADT vacations.
Greetings Gayo2007,
Please tell us your bio. Age? Location? When diagnosed? Treatment(s)? Treatment center(s)? Scores Psa/Gleason? Medications? Doctor's name(s)?
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THANK YOU AND KEEP POSTING!!!
Good Luck, Good Health and Good Humor.
j-o-h-n Monday 02/08/2021 5:04 PM EST
Gayo2007, Listen to J-O-H-N---we can best be of help, when we have all the numbers and facts--I would add any Unusual Description describing our Pathology, and have you on the way had Genetic Testing?
Nalakrats
Thanks Nal, I will add those to questions....
Good Luck, Good Health and Good Humor.
j-o-h-n Tuesday 02/09/2021 12:48 PM EST
Not to add on for no reason---just that almost every trial today has Immunology Targeted Drugs, or drugs alone or in combo going after some DNA repair mutation, or a pathway, like mTOR. To participate, the first thing these trials want is your Gene Mapping---at last I ran into some numbers, there was 3100 Trials World-Wide dealing with all cancers, related to Immunology.
Nal.
I Un-added those two questions.....I get fershimmeled easily nowadays.....
Good Luck, Good Health and Good Humor.
j-o-h-n Tuesday 02/09/2021 7:45 PM EST
"Unique Eunuch" or as my bicycling friends call me "Psycho Johnny" here giving 2 thumbs up for the "2 bawlz removal" as MY INITIAL TREATMENT UNDERTAKEN." Coming up to 6 years diagnosed with a chart topping Gleason 10 tumor contained but bet the cells are a roam'n just looking for a fertile "Location - Location - Location" to settle. Glad the boys are gone and NO REGRETS.
Lupron is chemical castration. If you wish to stop Lupron you could go for the orchiectomy.
Thanks