Can you be hormone sensitive and still have metastatic prostate cancer because during your remission you were off all
medications. Because pSA went up during you remission and now you are going back on ADT and Second line hormones does
this mean your castrate resistant just because it did metastasized . I am confused! Thanks
Yes, you can certainly be both hormone-sensitive and metastatic. For you, who are recurrent after prostatectomy there is evidence that advanced second-line hormonal therapy (or Chemo or Xofigo) is beneficial:
ascopubs.org/doi/full/10.12...
nejm.org/doi/full/10.1056/N...
ncbi.nlm.nih.gov/pmc/articl...
pubmed.ncbi.nlm.nih.gov/270...
He had radiation and Lupron not prostatectomy - does that matter
No - either way it is recurrent.
Just because one drug failed does not mean that other drugs would fail also.
Right and thankfully at this point he didn’t fail Lupron he was just not on it cause he was in remission and thought the cancer was cured.
Hop back on .
Thought you could cure whate ales us....put too sleep for while wich he did....but what we got aint g oin away..as i understand
Sorry....could not cure what ales us....lupron today....
Simple definition of hormone sensitive (androgen sensitive or castration sensitive ) is that these cancer cells die if you deprive them of testosterone.
OTOH, if the cancer cells do not die even after depriving them of testosterone then it is called Hormone Resistant or Androgen resistant or castration resistant.
Hormone sensitive or hormone resistance has nothing to do with whether it is metastatic or non-metastatic.
question if my dad was
Clean from
Mets 5 years ago and stopped the Lupron and now he has mets after 3
Years of
Nothing - is that too fast of
A spread or no
Zytiga and ADT 
Confused about a friend
effectiveness of zapping what is seen on PSMA scan
Just starting my voyage
A question and a bit of a gripe! 
