Not Time For Lu 177

[rhome502]

Just got the results from my c11 pet/ ct scan. The scan came back showing 1 small spot on the left side of my prostate bed. It is not enough cancer to do Lu 177. Dr. Lam thinks we can radiate that spot. Could that lead to an actual cure or a long remission.

[Magnus1964]

Radiation would be a good next step. It might be advisable to go on casodex before radiation.

[Tall_Allen]

I couldn't find your diagnosis in your profile. Do you have advanced prostate cancer?

[rhome502]

I currently classified as crpc. No Matisse to bone or soft tissue. Current PSA is .4. Treatments include Punch clinical trial at City of hope. Jevtana did not work. Radiation 70gy 35 sessions. Triple blockade that lasted 5 years. Provenge plus Xtandi PSA < 0.01 for over 2 years. Currently on Nubeqa. Current PSA .42. Original Gleason 4+ 5.

[Patrick-Turner]

X-ray beam radiation may or may not kill Pca that was not all removed in an RP. This is a very common procedure, and I am sad to say it often means you have a long fight with Pca and no remission, which is extremely unlikely unless ALL Pca cells abd ALL PG tissue was removed before any spread has occurred. It is often impossible to do X-ray radiation using a "pencil beam" because all EBRT, IMRT, or any type of beam radiation based on Xrays cannot be confined to a beam with tiny width, and all Xray beams flare out like a torch light in a smoky room, and damage is done to all places where beam enters and leaves the body, and quite high levels are needed to kill Pca cells, as I found out when I had 70Grey EBRT in 2010 and another 31Grey in 2016 to kill Pca in PG and around it.

I could not have an RP due to the local spread. But my Pca was radiation resistant, and use of Cosadex in 2016 during and after the salvation radiation DID NOT kill the remaining Pca in PG, despite boss doctor and leading hospital saying it would,

Most killing of Pca was done last year with Lu177, Psa went low, but its up again, so a 7th PsMa Ga68 scan will be done next week and maybe I get more Lu177.

Casodex masked any effect the salvation radiation might have had; Psa dropped from 6 to nadir of 0.4 then back up to 6 in 7 months. But more mets appeared in lymph nodes and bones in consequent PsMa scans. Zytiga didn't work for more than 8 months and chemo failed after 4 shots, hence I tried Lu177.

But I have survived 10 years+ after diagnosis with a Gleason 9.

I cycle 200km a week at age 73, average speed today for 53km was 24kph. I feel very well.

Patrick Turner.

[Walkingwell]

Thanks for your post. Interesting and inspiring because you have 'failed' chemo and Zytiga but not failed at all in important ways. I have some similar experiences (Gleason 9, failed chemo after 1st shot, Zytiga 2 months) but have a way to go before I'm cycling 200 km week! Best wishes.