Round 3 of docetaxal June 4th. I almost dont want it to end.

[Costarica1961]

I find myself wanting to hang on to treatment plans as time and treatment plans go by. Rad prostectomy 2016, 37 sessions rad 2017 zytiga lupron 2018 to 2019 stopped PSA soared, then xtandi and lupron stopped within a couple months. Currently cruising into round 3 of docetaxal 5 bone Mets detected that prompted chemo decision, L3 zapped by rad 6 months ago. I am very active I clam and golf and walk and bike the beach daily I have lost 100 plus pounds in the last 7 mos. I see a new M.o on June 30th Dr bears Ohsu, thank you Tall Allen for that recommendation. My current doc indicated blood work looks good my white blood cells are 25 from .5 wow off the charts, my PSA has went down from 7.9 to 2.7 as of 3 weeks ago, I have encountered very few side effects this far this is all good what should I expect going forward, the best case scenario a furthur drop in PSA with a long period of Mets slowed, then onward and upward to to clinical trials. Or perhaps another round of chemo when necessary. Just wondering as if I'm looking at a menu at a restaurant and I am on course number 5 and am trying to milk it until the final course.

[Schwah]

With only 5 mets, why not add SBRT to those mets to your menu? Assuming the locations are safe to go after. No proof yet that it prolongs life but many smart people from the best institutions believe it will be proven to do so.

Schwah

[Costarica1961 in reply to Schwah]

I actually had SBRT on my L3 vert 6mos ago when my first met popped up. Then 4 more followed, one on my humerus and one on my pelvic region as well as two small ones on the back of my cranium. I was told when I asked about zapping these Mets it's kinda like wack a mo, and the standard of treatment is chemo. My preference is get rid of those Mets but I thought once chemo begins it's already hitting those Mets? Should I push for SBRT Regardless? Thankyou schwah

[Schwah in reply to Costarica1961]

ncbi.nlm.nih.gov/pmc/articl...

On my MO’s recommendation, I had 3 mets and zapped along with systemic treatment (lupron/zytega/chemo) about 3 years ago. I went for a second opinion with Dr. Kishan at ucla who also agreed it was a good idea. No new mets yet. The thinking is for men with ogliometastatic disease (5 mets or less) it could prolong life or even be curative. There are ongoing studies right now to show the efficacy of this treatment. They think that perhaps the abscopal affect will be in play. That’s where the SBRT to the mets causes an increase in killer t-cells which then gobble up other micro mets. Lots of articles Out there and discussion on this site. The treatment is a piece of cake. Three sessions and zero side affects for me. You can’t do it in lieu of other treatment since it’s not yet proven but if it’s in a safe place to go after, I’d give it a try.

Schwah

[Costarica1961 in reply to Schwah]

Thankyou I have put a call into the rad oncologist . Wow it's pretty strange that I receive more info on the forum than from well paid and supposedly well informed docs.

[Hidden in reply to Costarica1961]

Strange indeed. Some doctors are closed off except to their path of SOC .

[Schwah in reply to Costarica1961]

Go to “SBRT” and “ ogliometastatic” on this site. Lots of discussion to read so you can be well informed when you speak to your Radiolgist. Don’t however make the mistake of doing SBRT in lieu of your systemic treatments.

Schwah.

[nobaday in reply to Schwah]

Yep I went for SBRT at C3 in my neck when my RO was recommending chemo. A year later C3 is clear...and no pain in the neck!! Minimal side effects for SBRT. I like selective killing! From what I see of chemo after Zytiga etc it’s quite often only a few months before PSA starts rising, or reoccurrence of Mets. I’m still on Zytiga 30 months in and my preference is to stay away from chemo and go for Lu177 or similar for my bone Mets when Zytiga stops working.

And any chance I have to do any SBRT I will jump at it but I had 9 or so Mets to start so not SOC unless I am in big pain.

[Hidden]

Hang in there Costarica!🙏

[Costarica1961 in reply to Hidden]

Thankyou I will

[j-o-h-n in reply to Costarica1961]

You lost 100 lbs? Do we now have to call you Costarica1861? or Less-Cost-a-rica1961? or Cost-no-longer-rica1961?

(in 7 months.....)

Good Luck, Good Health and Good Humor.

j-o-h-n Tuesday 06/02/2020 11:05 PM DST

[Costarica1961 in reply to j-o-h-n]

Costarica lighter will be fine.

[j-o-h-n in reply to Costarica1961]

Ok Costarica lighter (dropping the year 1961) my aim is to please....

Good Luck, Good Health and Good Humor.

j-o-h-n Tuesday 06/02/2020 11:23 PM DST