meben, alben and fenben dosages

[kapakahi]

has anyone seen any info on what the dosages are for mebendazole, albendazole and fenbendazole? Well, I know Panacur C/fenben is 222mg/gram - but I've never seen anything about what people take in mebendazole and albendazole dosages for the same effects as fenben.

[TFBUNDY]

The mebendazole dose recommended by Care Oncology is 100mg a day

[kapakahi in reply to TFBUNDY]

thanks!

[abmicro in reply to TFBUNDY]

I am reading on the posts that you should take it with an antacid called cimetidine to help with absorption of the tapeworm med. I am going to do that as soon as my mebendazole med arrives from mexico. Will do 100 mg daily for a month as I read on the forums, and then off 1 month switching to doxycycline antibiotic for a month. I will do the tapeworm protocol with existing meds I do now: zytiga (with decadron 0.5 mg) , xgeva monthly injections, crestor to control high cholesterol, and Metformin 500mg to control high blood sugar.

Reading on the posts that there is not much luck with any tapeworm therapy helping prostate cancer, but I am going to try it anyway while I am waiting for my next serious treatment, radiation / chemo or both. Cant hurt to try. Better than doing nothing. Read one blog from a guy named Joe Tippens who had success treating advanced small cell lung cancer with a tapeworm med.

I also read on the forums that a cholera vaccination from Canada my help with prostate cancer. May try that too after trying the tapeworm med. Wife has never been to the Canadian Rockies, so worth a tour.

[kapakahi in reply to abmicro]

this article proposes that cimetidine can significantly help the effectiveness of mebendazole and standard PC meds

Repurposing drugs in oncology (ReDO)—cimetidine as an anti-cancer agent

ncbi.nlm.nih.gov/pmc/articl...

(I could have sworn I pasted in that link but when I looked again it wasn't there, so I'm trying again...)

[TFBUNDY in reply to abmicro]

Yep. Cimetidine delays elimination of the mebendazole. I also had the Dukoral last week. Keep chipping away at it... Cheers

[nobaday in reply to abmicro]

How is the mebendazole working?? Im on Zytiga / Dexa with 0.01 PSA but in process of ordering mebendazoke/ fenbendazole.

[abmicro in reply to nobaday]

Dont know if it helped, but it did not hurt. Only used it a month before starting chemo. Might go back on it after chemo.

[kapakahi in reply to nobaday]

my PSA has dropped from 2.277 in June to 1.4 for the last 2-3 months - I started with fenben in June and switched to mebendazole in early December, 200mg with cimetidine twice a day with high-fat meals (well, the highest fat I eat). 1.4 is still quite a bit higher than it was in November 2018 - .09, and that itself was 50% higher than in August 2018. So it tripled in 8 months to 1.8 in April, then hit 2.277 in June, when MRI and Axumin scans showed the cancer had rejuvenated. That's when I found out about fenben and started it, and was gratified to see the PSA start dropping, but now it seems to have reached a plateau, so I don't know what that means since it's still more than double what it was in August 2018.

Keep in mind that I don't have mets so far - as far as I know - and haven't had to take any of the serious meds that guys here take. I know next to nothing about your meds, and I'm not at all sure about adding something like fenben/mebendazole to a medication regime like yours.

[nobaday in reply to kapakahi]

Hi kapakahi.

I’m on Zytiga/ dexamethasone 0.5mg

So the normal daily dose of mebendazole is 100mg/day as you have stated.

Yet you are taking 200mg mebendazole and 200mg cimetidine twice daily ie. 400mg mendazoke and 400mg Cimetidine daily.

Please explain rationale. Please give your dose rationale.

As long as PSA remains below 2 or so that seems great?! My PSA fluctuates <0.008 to 0.02 so basically undetectable but I did have a C3 met grow which I zapped by SBRT.

So your PSA is holding steady at around 1.4.

What other drugs and ADT are you taking?

So at the moment what do you think is causing your PSA plateau? Mebendazoke might be helping but at least no harm in taking?

I know a few guys on this site are taking fenbendazole or mebendazole but difficult to keep up with their progress.

Your thoughts? I have a friend currently in Mexico City who can get OTC 100mg mebendazoke for around $1 Canadian so I have asked him for 180 pills.

[kapakahi in reply to nobaday]

Well, I've always been a more-is-better guy - like in sex, pie, dope and surfing. But there's also the very low bioavailability of the benzimidazole drugs; that's one reason for taking the cimetidine with them -- slowing down digestion so they remain in the stomach longer and presumably more available. Whether it actually works that way, I don't know, but cimetidine has its own cancer-fighting properties. So I figure that if I take more, and it doesn't otherwise cause any harm, more of it might get into my blood and get transported to where I need it. So far, despite taking 4x the standard dose of both fenben and mebendazole since June 2019, my liver counts are fine and I don't have any intestinal issues.

I don't take any other PC meds, though my urologist suggested ADT, and he also suggested SBRT - I've declined both for now since I don't appear to have any mets and the cancer has never escaped the capsule in 12 years of having this crappy thing that totally upended my life (well, in combination with coronary artery disease, arthritis in all my joints from having too much fun surfing, and two bouts of melanoma, another gift from surfing). When I was diagnosed in 2008, the PSA was 8.8 (up from 4 in a month) and the Gleason was 4+3 = 7, and the doctors made me very afraid just when I had finally gotten my life on a good track. I guess I should get a biopsy but I've had so many I'm just kind of sick of them, plus I'm always on edge about PC cells escaping via that route. Hasn't happened yet (that I know of - but maybe it has and my immune system killed them), but I don't want to keep testing it.

As I said, a PSA of 1.4 is more than twice what it was in August 2018, when it started rising; it had been in the 0.6 area for three years following my last HIFU. When it hit 2.27 in June, scans showed the cancer had gotten going again, so my goal is to knock it back to where it was, meaning 1.4 is still too high - I want to see it back down to 0.6 or so. I don't know why it's stopped decreasing - maybe that's as far as mebendazole can take it? If it stays down there and periodic scans show no mets, I guess I'll live with it till something else gets me.

[nobaday in reply to kapakahi]

Kapakahi

Thanks for reply.

Looks like you are good and stable for now, and hopefully many months more!

If and when your PSA does double a couple of times you have ADT, second line ADT such as Zytiga (which has worked great for me) and a host of other options ( as detailed on this site).

All the best!

[donits]

Hi,

Several of my online colleagues take mebendazole at a doze of 100mg daily.

You may find more information at clinicaltrials.gov.

[kapakahi in reply to donits]

thanks!

[kapakahi in reply to donits]

do you happen to know where they buy their mebendazole and what their price is?

[donits in reply to kapakahi]

This is a prescription drug, also known as Vermox in Europe, is not expensive. Another medicine with similar effects in Europe is known as Pyrvin or Pyrvinium and can be bougth over the counter at pharmacies. What country do you live in?

[kapakahi in reply to donits]

the good ol' USA - there must be a way around the affordability issue other than flying to Europe and bringing home a backpack full of it - well, I just ordered some from India at about 25¢ per pill

[j-o-h-n in reply to kapakahi]

"meben, alben and fenben", sounds like the 3 Albanian stooges....

Good Luck, Good Health and Good Humor.

j-o-h-n Thursday 11/21/2019 6:48 PM EST

[donits in reply to kapakahi]

You can try politely to ask your doctor for a prescription. If your doctor is a woman, come with flowers

Do you have a proven source in India? Sometimes, false medicines occur. BTW, Fenben you van buy without a prescription.

[kapakahi in reply to donits]

Yes, I consider my source in India proven - never a problem, never bank fraud, the meds work, made by leading Indian pharma companies that make the meds for American Big Pharma. I decided to go with mebendazole because I'm finding it hard to get enough fenben from Amazon and the price is rising, sometimes they're out of stock. 3 doses of fenben on Amazon costs at least $12, so $4+ per dose, while I'm getting 750 100mg mebendazole pills from India for $193 - 25.7 cents per dose. I'm planning to take two per day, so I'm getting a year's worth. I really don't trust that it will be available an at affordable price forever, not with these bloodsucking fake drug companies whose business plan doesn't really include making the drugs, just buying the rights and jacking up the prices 1,000%. These anti-helmintic drugs are very cheap to make and cost very little everywhere but the US. These vampire CEOs belong in prison. (rant-rant-rant)

[donits in reply to kapakahi]

Hi,

Thank you for your post. Thank you for your post. Please, let us know how mebendazole will work.

Warmest greetings

[GIBasterian]

Amazon has goat dewormer, which is fenbendazole in liquid form. Very cheap! 125ml which corresponds to 125grams for $25.46.

The Joe Tippens Protocol is to use 1gram or more daily, ten times the 100mg Menbendazole people are talking about here. I am doing 1gram daily, or 1ml using a cheap hypodermic to pull it from the bottle. I put it in my green tea, hold my nose, and gulp. So my daily dose cost at 1gram is about 22 cents. Tippens says to do 3 days on, 4 days off.

TIPPENS PROTOCOL

A) 1 gram granules PANACUR (3 days on, 4 days off) of canine drug ‘Panacur C’, which contains 222mg of fenbendazole

B) Vitamin E Succinate (800IU daily) 7days

C) Curcumin (600mg daily) BIOAVAILABLE 7days

Merck-Safeguard-Goat-Dewormer-125ml

[kapakahi]

Well, check my math on what follows, but there are 222mg of fenbendazole per gram in Panacur-C granules, so that's a strength of 22.2%; the safe-guard liquid has 100mg per mL/g, or a strength of 10% (as the label states), so it is less than half the strength of the granules and the same dosage as in one mebendazole pill. If you're taking 1 mL (1g) of safe-guard per day, you're getting 45% of the daily dose recommended by Tippens.

My mebendazole pills cost 27¢ each and they each contain 100mg of mebendazole; your fenbendazole liquid has 100 mg of fenbendazole in 1 gram for 22¢, and if you want the 222mg of the Tippens protocol, you'll have to pay about 49¢ (but I'm terrible at math so check it yourself). Mebendazole pills are more convenient and they're sweet and chewable and, it seems, less than half the price of fenbendazole liquid (which itself is far cheaper than the $4 per dose cost of Panacur-C granules even though it's less than half the strength).

I've tried to find out if mebendazole and fenbendazole are of equal strength but I haven't been able to discover anything about that. Suffice it to say that 100mg is the standard dose for humans, depending on body weight and the type of worm, which is considerably less than the dose of fenbendazole used for animals. You can draw your own inference; I'm guessing that either mebendazole is stronger than fenbendazole or that humans just need less medication to kill the same worms that animals get.

Regardless, I'm taking 400 mg of mebendazole per day along with 200 mg of cimetidine, which helps the body absorb more of the drug.

The fenbendazole dose for animals seems to vary depending on the type of animal (like canine or ruminant), body weight and the type of worm. For some reason, dogs get a much higher dose than ruminants, maybe because the two different species of animals have very different digestive systems, so it's hard (at least for me) to compare the two forms of benzimidazole.