Netfotmin and Mebendazole: Just became... - Advanced Prostate...

Advanced Prostate Cancer

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Netfotmin and Mebendazole

lewicki profile image
19 Replies

Just became aware of taking Mebendazole a drug for hook worms etc..Also Metformin. Should these drugs be taken and advise your doctor that this is what you are doing?.

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lewicki profile image
lewicki
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19 Replies
lewicki profile image
lewicki

Will have to convince the MO to write it. She is interested in trying the high T should the radiation treatments begin to fail. She is open to trying things.

lewicki profile image
lewicki

Thank You.

Kaliber profile image
Kaliber

I’ve used metformin before and no biggie, worked well to control my bg. Not for a few years tho. I’m on Lupron - Xtandi- Zometa. My weight ballooned back up along with my bg , on adt, so doc put me back on metformin. Also on lisinopril- hydrochlorthiazide + amlodipine for bp.

Taking 250mg metformin in morning. Nearly instantly my bp dropped to scary dangerously low levels ... if I had taken the full 500 mg tab I would have likely ended up in E.R. . Near zero effect on my bg so far. Got to be careful with metformin and interactions .... could kill you ..

Peace brother ✌️

abmicro profile image
abmicro in reply to Kaliber

what is bg?

Kaliber profile image
Kaliber in reply to abmicro

Bg is blood glucose, .... finger diabetes tester.

Tall_Allen profile image
Tall_Allen

Of course, tell your doctor.

Kaliber profile image
Kaliber in reply to Tall_Allen

Absolutely my friend ...

She told me to take the half a 500 mg metformin, every other day for now to ease me onto it ... then if things look stable go to the daily regimen. She thought the reaction looked concerning but told me to watch it closely

Kaliber profile image
Kaliber

I’d been hanging around 138 / 82 or so for a while , 132 / 78 etc. ... ( well under the 150/90 allowed for old fat farts like me ) took the metformin and two hours later it was 97 / 68 ... of course that’s just low normal and is a good level ... but not normal for me at 73 and obese ... a few hours later I was measuring 110 / 89 .. never see my diastolic rise before ... and my Kardia was reporting atrial fibrillation yayahahahaya. Pulse had jumped to near 100 and I’m a low 60s kind of guy. Yikes ...

It’s a couple days later now and everything is pretty much back to normal , lost 10 off the systolic and about 6 off the diastolic.. first time in a while I’ve been in the green range for those for a normal person. Sys hitting just under 120 now and dia just under 80 every time .... love that. Now atrial fib gone too ( Kardia always reports me a non specific arrhythmia that doesn’t fit any of the algorithms including normal ) . My bp machine and my Kardia both integrate into my Kardia app which makes things very handy for storage and retrieval. Both do ekg algorithm analysis and can check each other too.

Looks like it’s going to be OK now , but if I had taken a full 500 mg or more , it’s hard to say where that would have went.

Peace Brother Nal ✌️

Schwah profile image
Schwah

google.com/amp/s/www.ajc.co...

Isn’t anyone concerned about this-tainted metformin?

Schwah

kapakahi profile image
kapakahi in reply to Schwah

well, I would be concerned if the FDA said it actually found excessive levels of NDMA in metformin as it has in blood pressure meds and stomach acid reducers. But the FDA didn't say that; it said it was investigating metformin to see if it has those excessive levels. And for now people should keep taking their metformin.

ncbi.nlm.nih.gov/pmc/articl...

"Metformin and cancer: An existing drug for cancer prevention and therapy" - the article reviews the recent science and notes that metformin has a direct anti-tumor effect, and that it has also shown some promise in killing cancer stem cells, including prostate cancer stem cells, which are responsible for tumor resistance and relapse.

I can't attest to the quality of these studies, of course. I take 2 grams of metformin daily in sustained-release caps. Been doing that for a few years for pre-diabetes - and still my prostate cancer revived itself.

To quote a former government official who should have been imprisoned: "...there are known knowns; there are things we know we know. We also know there are known unknowns; that is to say we know there are some things we do not know. But there are also unknown unknowns—the ones we don't know we don't know."

That pretty much applies to cancer treatments as much as it did Iraq, I guess.

Kuanyin profile image
Kuanyin in reply to Schwah

I'm concerned. After reading your post, I contacted Mylan the manufacturer of the form of Metformin (1000mg ER Osmotic Tabs) I take. I was told that there was no "current recall" of the product. I guess, we can assume, that it contains "acceptable levels" of the poison.

D_Alden profile image
D_Alden

Those are two of the off-label meds that Care Oncology prescribes as an adjunct therapy for cancer patients. Others are doxycycline and atorvastatin. The price of Mebendazole recently skyrocketed after being bought by a predatory investment company, but COC has a compounding pharmacist that dispenses a generic to their patients.

novatimo profile image
novatimo in reply to D_Alden

Correct. I've been on the Care Oncology protocol for the past year and taking the 4-drug regimen. You can read more about PCa and the CO protocol here: careoncology.com/the-coc-pr...

lewicki profile image
lewicki in reply to novatimo

Thanks for the link. Very interesting.

Ahk1 profile image
Ahk1

I couldn’t get my Uro and general dr to prescribe metformin. OFCOURSE, my MO in a large cancer center will not do it either, I didn’t even attempt to ask him. I started taking Berberine about 3 weeks now( 500 in the morning and 500 at dinner). I think I will continue to take it for another 2 1/2 months when I will be repeating the psa and see if there is any effect. If no impact on the rising psa, I will stop. I am not diabetic or pre diabetic. Starting today, I will start another experiment to take fenbendazole ( ordered from amazon) and try it also for another 2 1/2 months). If no effect from these supplements, then I will take the ADT route and start it.

PhilipSZacarias profile image
PhilipSZacarias in reply to Ahk1

I conduct similar trials - it is the only way to know what may be or not be effective. Nevertheless, it is best to make one change at a time otherwise you won't know which adjuvant contributed to the effect/response. If you go off berberine, then wait a month and see what the PSA trend is, then start fenbendazole. Alternatively, stay on berberine and then start fenbendazole. There may additive or synergistic effects. I have been on metformin and rosuvastatin for the last couple of years and these may have to contributed to a delay in my progression. PSA started going up a couple of months ago, so I added doxycycline and fenbendazole to the regimen two weeks ago - this is similar to what is referred to as the Care Oncology Clinic protocol. I will know in two weeks whether my PSA has stabilized. Cheers, Phil

Break60 profile image
Break60

I’ve been using metformin since 2015 among others meds. I’m doing well.

lewicki profile image
lewicki in reply to Break60

What is the dosage?

lewicki profile image
lewicki

good luck.

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