Bitter taste on Zytiga?

[Life5]

Hello,

My dad takes 4*250 mg of Zytiga (Abiraterone) tablets immediately on waking up in the morning, has tea and breakfast after an hour and one 5 mg of prednisone with his afternoon lunch. He also had 3 monthly zometa infusion 12 days ago and witnessed flu like symptoms, nausea for a week. He has been having the usual side effects such as fatigue and hot flushes. Recently, he has been complaining that what all he eats during lunch tastes bitter, but the same issue is not faced while having dinner.

What all i have read online shows having a bitter/metallic taste is common on docetaxel and other chemo drugs - i cant find anything similar on Zytiga - anyone has any experience on the same? Is it a normal side effect from Zytiga? I would appreciate any help.

Thanks

Age 75.5 years, Dx on 24/06/19 - initial PSA - 114 .16 ng/ml, Gleason 4+4=8, perineural invasion with rectum involvement more on right side, PSMA Pet scan - mets to several lymph nodes right up to behind the neck, only 1 bone met on pubic bone

12/07/2019- Orchiectomy and Bicalutamide (Casodex/Caluran)

03/08/2019- PSA down to 4.66 ng/ml from 114.16 ng/ml

10/08/2019 - Commence Zytiga generic and prednisone

06/09/2019- PSA down to 0.837 ng/ml

07/09/2019- first 4 mg zometa infusion

[6357axbz]

Zero taste issues with abiraterone for me. Prednisone can be very bitter if not swallowed quickly with a good gulp of water. Don’t let that pill linger in your mouth.

[Life5 in reply to 6357axbz]

Thanks a lot 6357axbz. It indeed seemed to be the prednisone. He is now taking it post his lunch with a glass of water and it has seemingly helped with controlling the bitter taste