Hello,
Just saw dad's MO today. PSA is doubling every month and is currently at 0.22. Scans that include CT, bone and MRI came back unchanged from November 2021. Regardless MO believes the cancer is active again as dad's symptoms (frequent peeing, extreme fatigue) are getting worse. He has offered zytiga and radiation of the prostate. MO mentioned there is no guarantee Zytiga even works, and if it does work, he might get 4-5 months out of it. The radiation is for palliative purposes to hopefully help with the symptoms. Radiation to lungs/liver is not possible due to the number of mets there. He also said docetaxel is on the table as well. He started with this treatment in July 2021 and it was really effective as lung and liver mets greatly decreased but he had pretty bad side effects.
Based on what I've read, it seems to be the right steps. I'd love to hear your thoughts.
Also, anyone have information on when LU177 would be available in Canada? More specifically Ontario.
Thanks,
If he handled docetaxel without too many SE's. it may be worth a re-challenge with it and the addition of zytiga can really help. With my first BCA the ALP climbing was first sign. It climbed for 6 mo. before PSA went up and new bone mets were evident with Na-F18 scan. Here's hoping the zytiga and RT will hold his aPca back for an extended period.
Just looked at his ALP, it is rising like his PSA but a much slower rate. I hope the Zytiga keeps the cancer inactive for a year+ like many here.
Zytiga a good choice. Another option is enzalutamude (Xtandi). I began Xtandi when my PSA began rising 2 years after Docetaxel. I had good results for around 15 months. PSA may be rising slowly again but there are no other signs of progression. Another round of chemo is another possibility. Keep in mind that each case is different. Rely on your MO for advice and ask about all the options. The MO will have all the details of your father’s case.