Some of my musings on the safety of fenbendazole reached the ears of the guru himself, Joe Tippens, and his response was:
"I have done two man-years of research, including numerous scientific studies AND human toxicity studies. The human toxicity trials conclude that less than 500mg per day long-term is completely safe. In most cases, the entire class of anthelmintic drugs were included in the studies.
I am absolutely sure the cautions are for legal reasons. We have hundreds of people globally taking FZ daily for 3 years now and the only side effects reported thus far are (i) about 5% of the people report elevated liver enzymes and (ii) about 10% of the people report mild diarrhea. Neither is clear whether it is absolutely sure that it is the FZ that caused the side effects.
Johns Hopkins University is the institution that did the toxicity trial in conjunction with a human clinical trial for brain cancer. The brain cancer trial was for the sister anthelmintic Mebendazole but the toxicity trial included both
I now have over 50 success stories and the attached research shows exactly why it works and why it appears to be cancer agnostic. [Enclosed was a 15-page report from nature.com/scientific reports titled Fenbendazole Acts as a Microtubule Destabilizing Agent . . . -- I already had it on file]."
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cigafred
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Yup. And apparently the Merck price has DOUBLED since Joe Tippens went public with his story. He paid $4 a week. So I ordered a year's supply. The protocol is 3 days on 4 days off. But to kick start the protocol, my husband did daily for 2 weeks. Then went to the 3/4. If you are interested in starting I would recommend going to mycancerstory.rocks for Joe's complete story. There is also a FB group of the same name. It's a private group - the password is given on the blog mentioned above.
I use Safe-guard4 fenbendazole in the green box. Same exact formula as Panacur C. Last time I ordered it, it was only $5.16 for a box of 3 from Amazon.com. I looked this morning and the price has doubled!
Thanks, started with the powder, but takes forever to get here from the US. Now using the liquid for livestock which is supplied in Aus. Half teaspoon almost equivalent to 225 mg, a bit over. Mash it into guacamole. A lot cheaper... I imagine the Merck version will continue to escalate.
Talked to my oncologist last trip, he did not discount the possibility of it working, funny he was aware of the stuff. Always knew he was ahead of the game and a good doctor. 😜😜
I had assumed that at 100 mg/ml one should take 10 ml so as to have the same one gram dose??
Per Joe’s blog the fenben should be taken with fat to increase bioavailability. After downing it with water, I have coconut milk in a mocha, lots of plant based fat in that. Or, 1 Tablespoon of olive oil.
I'm taking the 4-g dose for big dogs because, well, I'm bigger than a Yorkie. The 3-packet box cost $16.68 on Amazon (1 g is $8.20 - these prices are Amazon Prime with "free" shipping, meaning they just raise the price of the item you're buying). So the 4-g dose is 222 mg.
In late June I took it for two consecutive weeks, 3 days on, 4 days off - a month later my PSA had dropped from 2.27 to 1.8. But that could be just a normal variation since PSA can move around like that depending on all kinds of factors - that was a drop of only about 25%. So I've just started a cycle again, going for a month, and this time I'll get a PSA test immediately after.
I wasn't going to tell my urologist until I had a result I could maybe rely on - like a definite downward dip. But at my last visit, my wife was with me, and she asked me, "Aren't you going to tell him about...you know, what you're taking?" Grrr! (At least she apologized all the way home - she hadn't heard me say I wasn't going to tell him.) So I had to tell him - he was kind of dumbfounded, I could tell - he'd never heard of fenbendazole - but he didn't lecture me or anything, just listened. (I'm a new patient - the guy who took care of me for the 11 years I've had PC retired.)
I'm due for a biopsy - either regular ultrasound or MRI-guided. We're pretty sure the PC has regenerated since my PSA went from below 1, where it had been for about 4 years, to 1.8 in 5 months and then 2.27 a month later. Since fenbendazole is supposed to kill cancer, not just lower PSA, I'm hoping for the best.
I am interested to know how you are faring under Fenbenz. I am struggling with doubling PSA in 2 weeks. Need to arrest the PSA rise. Appreciate your views since you have tried it.
Keep in mind I'm no doctor, have no science background, and just like most guys here, I just read and experiment on myself a lot. And I probably shouldn't even be on this forum since I've never had advanced PCa - I just showed up because it was the first forum I found and didn't even notice the name is "advanced."
With that rate of doubling, and not knowing your history, I'm not sure it's wise to wait for fenben to work.
It seems to be working for me. My last PSA test was on Aug. 14, after I'd done another month 3 days on 4 days off - the count dropped again, this time to from 1.8 to 1.5. That's lower than what it doubled to the first time (0.9 last November to 1.8 this April, then 2.27 in May), so that's encouraging - I've never had it drop after doubling. I've been taking fenben since then, same 3/4 schedule, due for another PSA next week. I'm hoping for the best. Since the last one I've added 4 other supplements that I've read about here that have at least some research behind them, though I can't attest to the quality of that research - IP6 & Inositol, DIM, artemisinin, and sodium butyrate. So if it drops again, I won't be able to tell how much to credit fenben - and I don't really care as long as it keeps dropping - but I'll feel more assured that fenben is playing some role. Because the PSA is dropping, I haven't had a biopsy yet - that can skyrocket PSA and keep it elevated for weeks. I'm pretty sure it would show at least some cancer.
But your PSA doubled in 2 weeks (from what to what?) - mine doubled in 5 months, and I'd never had any metastasis over the 11 years I've had PCa.
If you haven't tested for free PSA, you should - it's a fairly reliable indicator of cancer - the less free PSA you have, the higher the odds that cancer is causing the rise (en.wikipedia.org/wiki/Prost.... If the results are worrisome, you might ask your doctor about getting an Axumin scan (en.wikipedia.org/wiki/Fluci....
From what I've read fenben seems to start working fairly quickly, and Joe Tippens says he had only a few weeks or so to live when he started. But he'd already been through the gamut of treatments over a period of years (he had small cell lung cancer, not prostate cancer). If you want what's probably the highest level of knowledge here (including more than some urologists seem to have about PCa), check out guys like Tall Allen, pjoshea13, greg57, cesanon, namakrats...Tall Allen especially is a well-informed skeptic of poorly or insufficiently researched treatments.
I am 12.5 years post diagnosis, with metastasis to bones at diagnosis and PSA of 800+. After exhausting all ADT options was last on Zytiga, which stopped working about 5 months ago dipping to the lowest PSA of 0.2. Today it is 10.5. In nutshell that's my case. Your Fenbenz experience is very encouraging and I am seriously considering emulating you, although concerned about toxicity, especially liver+ kidney which is already under severe stress. Am trying to put togather a protocol based on what you have reported on this forum so far. Any additional and specific information you or the wise ones on this forum can provide will be invaluable, although I understand that every person and every PCa can be individual. If it works for some of us, many more will be encouraged to follow in our footsteps.
Read Joe Tippens's blog - he was kind of in your situation, maybe more dire. He started with the fenben three years ago, I think, and is still taking it. Basically, he said mets lit him up like a Christmas tree, and now...gone. I think he's taking a gram a day to keep it at bay, and doing well. From what I've read here and elsewhere, fenben doesn't harm the liver or kidneys. But read Joe Tippens - he's got a lot of knowledge and experience. Fenben doesn't work for everybody, but it seems to work for some at least. Also search on this site for IP-6 & Inositol and DIM.
This is a link to some of the research that's been done on fenben - I found it on the website Trecento posted below about the pill form. I know nothing about that company - don't know that I'd trust them with something so important. I guess I do trust Merck to make the genuine, pure product. The site has this disclaimer: "FENBENCUR™ is NOT associated, endorsed, affiliated or sponsored by Joe Tippens"
I've found Panacur very easy to take - I just shake the contents of a packet into my mouth (so I briefly have a mouthful of granules which I show my wife like I'm a typical 8-year-old boy and she goes "Ewww!") and drink something, like a smoothie, with it, it immediately dissolves. Zero taste, zero digestive reaction. That seems logical given the way it works, against cancer the same way as against worms - it prevents cell division (mitosis) by disrupting something called microtubles inside the cell. This happens to be exactly the way the taxane chemo drugs work, though fenben does it without those drastic side effect. And it restricts the cell's uptake of sugar (cancer cells love sugar/glucose because they're growing so fast). Anti-Worm drug, Fenbendazole, effective at killing cancer cells | CANCERactive 2
Even in our darkest days, humans still manage to find hope, even if it's small and hidden. That's what gets us up in the morning. So visualize hope from all the people here as a glowing ball of light kind of blowing under your door into the air surrounding you, for you to breathe in and absorb. Maluhia* to you.
Asked cats if they would wear flea collars. Absolutely not. Unanimous. I do find liquid for livestock to be intriguing. Sounds like a one up on dogs and goats. Where will it end. No offense intended. I shall probably be buried by people who then sit to rest their weary hooves and claws.
I saw one person with prostate cancer success on the blog. Just applied for the facebook group but hope board members here will post their experiences with Fenben like some have done already.
My husband started Fenben on September 3. His PSA was stable last time when it had been rising. He is just taking the Fenben not the rest of the protocol as I research the Vit E and curcumin with prostate cancer. He also started Zytiga a month earlier but it didn't lower his PSA until coincidentally he started Fenben.
Hi guys I’m new on here. My husband has stage 4 prostate cancer that spread to the bone. He was diagnosed September 2018. His has 6 months of chemo followed by radiotherapy. A very tough journey but he got through it. His been taking the Fenbendazole powder for 3 weeks now with all the vitamins. He does 3 days on and 4 days off. He is experiencing really bad stomach cramps and diarrhoea and basically feels really ill. Can anyone tell me if this is normal please coz I’m really worried about him. Btw his taking 1 panache powder 4.5g which contains 999mg Fenben daily for the 3 days. Is this the right dose?
We may be the exception. My husband started on Zytiga in Feburary 2019. His PSA was dropping until it got around 10. At his diagnosis, it was 3200! He started taking the fenben in August, and since then his PSA went up to 13 and then to 15. I went on to the Zytiga site, and it listed drugs that could negatively interact with Zytiga, and many of them ended with azole. I'm panicking that I may have done him some harm, but the strange thing is, he said he never felt better since he started this terrible journey. We have stopped the fenben and are awaiting his December appointment to see if maybe his PSA will start dropping again.
I don't think Joe would want to be put in the position of telling any of us what drugs will interact with fenbendazole. He has stated that there are success stories with prostate cancer and I am sure there have been. That's why I had so much hope. I haven't given up yet. I read somewhere on this site that dying cancer cells can actually cause the PSA to rise. Maybe that is what was happening? My husband has never looked or felt better since starting the fenbenz. I'm just so torn because I don't want to hurt him.
Good advice, cigafred. I'll have to do that after his next appointment in December if we decide to start up the fenden again. I know many men on this site are using it. Hope if any of them are taking it with Zytiga, they'll give their results.
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