New Taxotere in pill form

[Magnus1964]

There might be a new form of Taxotere coming out but it is in pill form. Something there came out of the American Urological Association conference in Chicago. Don't know a lot about it. just something I thought the group would like to know.

[NPfisherman]

This is, I believe, MM-310 in Phase1/2 study. It is a liposomal version of docetaxol that shows higher tumor target specificity--not so random and likely, higher efficacy... Here's hoping...

Fish

[Hidden]

Note: “CAMBRIDGE, Mass., April 4, 2019 /PRNewswire/ -- Merrimack Pharmaceuticals, Inc. (Nasdaq: MACK), an oncology company focused on biomarker-defined cancers, today announced the Company is discontinuing development of MM-310, its antibody-directed nanotherapeutic for the treatment of solid tumors. This decision was the result of a comprehensive review of available safety data from its Phase 1 study. Based on emerging data since the recent amendment of the clinical protocol, the Company has concluded that the study would not be able to reach an optimal therapeutic index for MM-310. Merrimack has terminated the study and expects to initiate a workforce reduction as it closes out clinical activities, reflective of its narrowed preclinical pipeline and in line with prior cost-cutting measures.”

An aside comment. I don’t really know how an oral would tackle micro-metastatis in the lymphatic and vascular system. It was developed and trialed for “solid tumors” only and would do little for future tumors. And that I believe is why MM-310 trials are cancelled.

Keep kicking the bastard.

Gourd Dancer