47% Anti-tumor effect of Vitamin C, lysine, proline, arginine, and Ecgc (green tea) on metastasized PCa cell lines PC-3, LNCaP, and DU-145

[George71]

"showed dose-dependent inhibition of DU145 cell proliferation with 47% reduction at 1000 microg/ml. NS showed a dose-dependent inhibition of both MMP-2 and MMP-9 expression by PC-3 cells and MMP-9 expression by PMA-treated (200 ng/ml) DU145 cells. Neither MMP-2 nor MMP-9 gelatinolytic activity was detected in LNCaP cell culture. Invasion of DU145 and LNCaP cells through Matrigel was completely inhibited at 500 microg/ml and PC-3 at 1000 microg/ml. Inhibition of MMP expression and invasion suggests the mixture of nutrients studied is a potent, natural anticancer agent for the treatment of prostate cancer."

ncbi.nlm.nih.gov/pubmed/175...

[pjoshea13]

George,

'Matthias Rath' rings warning bells in my head.

en.wikipedia.org/wiki/Matth...

-Patrick

[George71 in reply to pjoshea13]

Apparently that was the reason the various tests were ran -- to see if a combination of adjutant supplementals had any therapeutic benefit.

" Based on the Rath multitargeted approach to cancer using natural substances to control ECM stability and enhancing its strength, we developed a novel formulation (NM) of lysine, proline, ascorbic acid and green tea extract that has shown significant anti-cancer activity against a number of cancer cell lines."

"These results together with our earlier findings suggest that NM is a relatively non-toxic formulation, which inhibits growth, invasion, metastasis, and angiogenesis of tumor cells."

ncbi.nlm.nih.gov/pubmed/161...