About a year ago I wrote here that three treatments with Keytruda had reduced my PSA to "undetectable (<.10)". Later I had a terrible sinus infection, big headaches, and my to be cautious, my oncologist stopped Keytruda (the docs thought maybe the headache was a reaction to Keytruda). Well, no matter. Eight days of IV antibiotics took care of the sinus problem. A year later, PSA is still undetectable. (WooHoo!!)
There's just one problem. My testosterone is also undetectable. Which means not only are the testes doing nothing, neither are the adrenals. A battery of tests revealed no other hormonal issues. So, do any of you folks know anyone who was on ADT for TEN YEARS and recovered normal testosterone? (Yeah, I know, most guys on ADT that long have passed.)
Best regards, and keep up the fight!
Written by
gvweller
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It’s great news really. I’ve been undetectable with adt for 3yrs but I did orchiectomy 9-16 also. My “T has been steady at 3 .. if I ever feel like trying “T” I’ll need to inject it. Testosterone for us is dammed if you do ,dammed if you don’t.. My layman’s opinion only ..
Wow. Radical prostatectomy, salvage radiation to the pelvic bed, ADT, Casodex, Xgeva, radiation to left shoulder, Zytiga+steroids, Xtandi, total reverse shoulder replacement. You can tell that the shoulder (and humerus) were a big problem. About the time we were considering Provenge, there was a substantial spontaneous regression, so Provenge was never used, then Zytiga became available. All the above was over a period of ten years. Often the doubling time was down around 30 days. When Xtandi failed, they sent me to Ann Arbor for a clinical trial. Genetic testing there showed that Keytruda would probably work. It did. I'm a lucky guy.
Congrats! Keytruda is working on my melanoma lung cancer also. ($30K per injection)
Good Luck, Good health and Good Humor.
j-o-h-n Monday 03/11/2019 2:16 PM EDT
After 6 years of Lupron/Eligard and a 6 month chemo trial with two different infusion drugs plus 5 different orals, my T never came back. I stopped ADT in February 2010...... well my PSA is still undetectable and the Mets are long gone. A year later in 2011, my Medical Oncologist put me on 4 mg of Androgel twice a week in an effort to jumpstart T. Never happened. I remain in low dose testosterone gel..... T ranges from 350 to 750 depending when I apply the gel and have my quarterly blood draw.
Count your self lucky that T is less than 5 and PSA is less than <0.1......... Good job.
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Now Undetectable PSA on BAT Regimen
Neuroendocrine prostate cancer
"Undetectable" 
I fired my oncologist
Recurrence with undetectable PSA?
