In 2016, I had three months of Firmagon followed by six months of Lupron as part of cyberknife treatment of my prostate cancer recurrence. Within four or five days of first Firmagon shot I started having hot flushes. My PSA dropped from 1.8 to 0.2 after the second Firmagon shot. By the time I had the first three-month Lupron my testosterone must have already reached castration level. The hot flushes did not completely go away year after the last Lupron shot.
On November 16 this year I started taking Casodex and then on November 30 I had the first Lupron shot. I was told that Casodex does not usually lead to hot flushes. But I started having hot flushes just a few days after starting Casodex. This morning, I had a very intense hot flush. How unusual it is to have strong hot flushes only after a few days of the first Lupron shot? I am curious to know whether there are other men with similar experience.