Can interact paroxetine with zytiga

[joancarles]

Does anyone have any knowledge or experience of interaction of paroxetine (antidepressant) with Zytiga?

[tango65]

"abiraterone + paroxetine

abiraterone increases levels of paroxetine by affecting hepatic enzyme CYP2D6 metabolism. Use Caution/Monitor. Avoid coadministration of abiraterone with substrates of CYP2D6. If alternative therapy cannot be used, exercise caution and consider a dose reduction of the CYP2D6 substrate."

reference.medscape.com/drug...

[joancarles in reply to tango65]

Thank you very much for the reply. I will look for a solution

[cs1037cs]

was on zytiga for two years and it work ok for me and then it stoped and i move to the next