Can interact paroxetine with zytiga - Advanced Prostate...

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Can interact paroxetine with zytiga

joancarles profile image
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Does anyone have any knowledge or experience of interaction of paroxetine (antidepressant) with Zytiga?

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joancarles
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tango65 profile image
tango65

"abiraterone + paroxetine

abiraterone increases levels of paroxetine by affecting hepatic enzyme CYP2D6 metabolism. Use Caution/Monitor. Avoid coadministration of abiraterone with substrates of CYP2D6. If alternative therapy cannot be used, exercise caution and consider a dose reduction of the CYP2D6 substrate."

reference.medscape.com/drug...

joancarles profile image
joancarles in reply to tango65

Thank you very much for the reply. I will look for a solution

cs1037cs profile image
cs1037cs

was on zytiga for two years and it work ok for me and then it stoped and i move to the next

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