My journey with Abiraterone looks like it has come to an end. Last week I was informed after 10 months on Aberaterone, that it is not as effective as hoped and that I would most likely benefit from a change in treatment. My PSA has gone from 68 down to 24 in that time with bone mets reduced but there is still activity. I have been offered an immunotherapy phase 1A trial at the Royal Marsden (London), which sounds interesting but obviously holds no promises. I still have Chemo, Radiotherapy and other options in reserve, but the specialist are very keen at this stage to see how I respond to the trial. The trial would include weekly checks, a drug taken orally and an IV drug taken once a month.
Would be interested to hear experiences of clinical trials, up and downs etc.